Aksakal Ceyhun, Şahin Mehmet
Tokat State Hospital, Department of Otolaryngology, Tokat, Turkey.
Tokat State Hostital, Department of Biochemistery, Tokat, Turkey.
Pan Afr Med J. 2019 Apr 2;32:154. doi: 10.11604/pamj.2019.32.154.18372. eCollection 2019.
the aim of this study was to investigate the possible relationship of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) and routine hematological parameters with recurrent epistaxis in children.
İn this retrospective case-controlled study, 294 patients aged between 2 and 18 years who applied to the Tokat State Hopital Ear Nose Throat Clinic due to recurrent epistaxis between January 1t 2013 and December 31 December 2017 and 329 sex-and age-matched controls were investigated.
NLR was 1.45±0.75 in the study group and the 1.35±0.7 in the control group. There was no significant difference between the groups (p>0.05). PLR values were found significantly (p<0.05) higher in the study group than in the control group (103,21±29.57 vs. 97,3±30.38). Red Blood Cell Distribution Width (RDW) values were found significantly (p<0.05) lower in the study group than in the control group (39,56±2,87 and 38,92±2,46).
the increase of PLR, an inflammatory marker, in epistaxis supports the effect of inflammatory factors in the etiology of epistaxis. However, more study in future is needed to support this.
本研究旨在探讨中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）及常规血液学参数与儿童复发性鼻出血之间可能存在的关系。
在这项回顾性病例对照研究中，对2013年1月1日至2017年12月31日期间因复发性鼻出血到托卡特州立医院耳鼻喉科就诊的294例2至18岁患者以及329例性别和年龄匹配的对照组进行了调查。
研究组的NLR为1.45±0.75，对照组为1.35±0.7。两组之间无显著差异（p>0.05）。研究组的PLR值显著高于对照组（p<0.05）（103.21±29.57对97.3±30.38）。研究组的红细胞分布宽度（RDW）值显著低于对照组（p<0.05）（39.56±2.87和38.92±2.46）。
鼻出血中炎症标志物PLR的升高支持炎症因子在鼻出血病因中的作用。然而，未来还需要更多研究来支持这一点。
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