Gumus F, Solak I, Eryilmaz M A
Bratisl Lek Listy. 2018;119(2):116-119. doi: 10.4149/BLL_2018_023.
The aim of this study was to compare the Neutrophil to Lymphocyte ratio (NLR), Platelet to Lymphocyte ratio (PLR) and Mean Platelet Volume to Platelet (MPV/Plt) ratio of smokers and non-smokers.
Two hundred smokers and two hundred non-smoking healthy volunteers were enrolled in this study. Sociodemographic data and hematologic parameters of all patients were recorded. NLR, PLR and MPV/Plt ratios were calculated.
The mean age of the case group was 35.88 ± 10.56 and the mean age of the control group was 38.97 ± 10.56. 80 % (n = 160) of the smokers were male and 20 % (n = 40) were female. 27.5 % (n = 55) of the control group were male and 72.5 % (n = 145) were female. The smoker group had higher NLR and MPV/Plt ratio (p < 0.05). PLR was significantly higher for the non-smoker group (p < 0.05).
As a result of our study, an increase in the NLR which is used as a systemic inflammatory marker, a decrease in the PLR and an increase in the MPV/Plt ratio which indicates thromboembolism risk were found for the smoker group (Tab. 3, Ref. 32).
本研究旨在比较吸烟者和非吸烟者的中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）以及平均血小板体积与血小板比值（MPV/Plt）。
本研究纳入了200名吸烟者和200名不吸烟的健康志愿者。记录了所有患者的社会人口统计学数据和血液学参数。计算了NLR、PLR和MPV/Plt比值。
病例组的平均年龄为35.88±10.56，对照组的平均年龄为38.97±10.56。吸烟者中80%（n = 160）为男性，20%（n = 40）为女性。对照组中27.5%（n = 55）为男性，72.5%（n = 145）为女性。吸烟组的NLR和MPV/Plt比值较高（p < 0.05）。非吸烟组的PLR显著较高（p < 0.05）。
我们的研究结果显示，吸烟组作为全身炎症标志物的NLR升高，PLR降低，以及表明血栓栓塞风险的MPV/Plt比值升高（表3，参考文献32）。
