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内镜下鼻胃管置入术治疗胃癌根治术后良性输入袢梗阻:一项16年的单中心回顾性研究。

Endoscopic nasogastric tube insertion for treatment of benign afferent loop obstruction after radical gastrectomy for gastric cancer: A 16-year retrospective single-center study.

作者信息

Cao Yuning, Kong Xiangheng, Yang Daogui, Li Senlin

机构信息

Department of Digestion.

Department of Gastrointestinal Surgery, Liaocheng People's Hospital, Liaocheng, Shandong Province, China.

出版信息

Medicine (Baltimore). 2019 Jul;98(28):e16475. doi: 10.1097/MD.0000000000016475.

Abstract

Afferent loop obstruction is an uncommon complication associated with Billroth-II distal gastrectomy. Inappropriate treatment may result in life-threatening events as perforation and peritonitis. For the benign afferent loop obstruction, Braun or Roux-en-Y reconstruction has been reported as the choice. However, the edematous afferent loop may result in anastomotic fistula. In this study, a less invasive technique was described for treatment of benign afferent loop obstruction. The aim of this study was to investigate the effectiveness and safety of endoscopic nasogastric tube insertion for treatment of benign afferent loop obstruction.We conducted a retrospective review of the data of 2548 gastric cancer patients who underwent distal gastrectomy from January 2002 to January 2018. Patients who developed benign afferent loop obstruction were treated by this procedure. Outcomes were recorded. Follow-up was scheduled at 3, 6, and 12 months after the treatment.Twenty-six patients (1.0%) developed afferent loop obstruction. The median age, consisting of 19 men and 7 women, was 60 years (range 36-69 years). Of these 26 patients, 23 underwent the endoscopic treatment. The obstructive symptoms had a rapid relief in all the 23 patients. No one died due to this procedure. However, 2 patients underwent surgical treatment due to intestinal obstruction because of adhesion at >4 and 7 months after the endoscopic drainage, respectively.Endoscopic nasogastric tube insertion is an effective and safe procedure for treatment of benign afferent loop obstruction. In addition, it could be considered as the first step in treatment, especially in high-surgical-risk patients.

摘要

输入袢梗阻是毕罗Ⅱ式远端胃切除术后一种罕见的并发症。治疗不当可能导致诸如穿孔和腹膜炎等危及生命的情况。对于良性输入袢梗阻,据报道布劳恩或 Roux-en-Y 重建术是治疗选择。然而,输入袢水肿可能导致吻合口瘘。在本研究中,描述了一种用于治疗良性输入袢梗阻的微创技术。本研究的目的是探讨内镜下鼻胃管置入术治疗良性输入袢梗阻的有效性和安全性。我们对 2002 年 1 月至 2018 年 1 月期间接受远端胃切除术的 2548 例胃癌患者的数据进行了回顾性分析。发生良性输入袢梗阻的患者接受了该手术治疗。记录了治疗结果。治疗后 3 个月、6 个月和 12 个月安排了随访。26 例患者(1.0%)发生输入袢梗阻。其中男性 19 例,女性 7 例,中位年龄为 60 岁(范围 36 - 69 岁)。这 26 例患者中,23 例接受了内镜治疗。所有 23 例患者的梗阻症状均迅速缓解。无患者因该手术死亡。然而,分别在接受内镜引流后 4 个月和 7 个月,有 2 例患者因粘连性肠梗阻接受了手术治疗。内镜下鼻胃管置入术是治疗良性输入袢梗阻的一种有效且安全的手术。此外,它可被视为治疗的第一步,尤其是对于手术风险高的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1316/6641837/ac67f2d33dcb/medi-98-e16475-g001.jpg

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