Medical University of Gdansk, Department of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Poland, Hallera 107, 80-416, Gdańsk, Poland.
Polpharma Biologics, 3 Trzy Lipy 3, 80-172, Gdańsk, Poland.
Anal Chim Acta. 2019 Oct 24;1077:14-29. doi: 10.1016/j.aca.2019.05.024. Epub 2019 May 15.
Electronic nose (enose, EN) and electronic tongue (etongue, ET) have been designed to simulate human senses of smell and taste in the best possible way. The signals acquired from a sensor array, combined with suitable data analysis system, are the basis for holistic analysis of samples. The efficiency of these instruments, regarding classification, discrimination, detection, monitoring and analytics of samples in different types of matrices, is utilized in many fields of science and industry, offering numerous practical applications. Popularity of both types of devices significantly increased during the last decade, mainly due to improvement of their sensitivity and selectivity. The electronic senses have been employed in pharmaceutical sciences for, among others, formulation development and quality assurance. This paper contains a review of some particular applications of EN and ET based instruments in pharmaceutical industry. In addition, development prospects and a critical summary of the state of art in the field were also surveyed.
电子鼻（EN）和电子舌（ET）旨在尽可能模拟人类的嗅觉和味觉。传感器阵列获取的信号，结合适当的数据分析系统，是对样品进行整体分析的基础。这些仪器在分类、区分、检测、监测和分析不同类型基质中的样品方面的效率，在科学和工业的许多领域得到了应用，提供了许多实际应用。这两种类型的设备在过去十年中的受欢迎程度显著增加，主要是由于其灵敏度和选择性的提高。电子传感器已被用于制药科学，用于制剂开发和质量保证等领域。本文综述了基于 EN 和 ET 的仪器在制药工业中的一些特殊应用。此外，还调查了该领域的发展前景和技术现状的批判性总结。
