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全髋关节置换术长期随访临床疗效的系统评价

Systematic review of the clinical effectiveness for long-term follow-up of total hip arthroplasty.

作者信息

Smith Lindsay K, Dures Emma, Beswick A D

机构信息

Department of Trauma and Orthopaedics, Weston Area Health NHS Trust, Weston-super-Mare, North Somerset, UK.

Centre for Health and Clinical Research, University of the West of England, Bristol, UK.

出版信息

Orthop Res Rev. 2019 Jul 2;11:69-78. doi: 10.2147/ORR.S199183. eCollection 2019.

Abstract

Total hip arthroplasty (THA) is highly successful but national registries indicate that average age has lowered and that younger patients are at higher risk of revision. Long-term follow-up of THA was historically recommended to identify aseptically failing THA, minimising the risks associated with extensive changes, but follow-up services are now in decline. A systematic review was conducted to search for evidence of the clinical or cost-effectiveness of hip arthroplasty surveillance. The study was registered with PROSPERO International Prospective Register of Systematic Reviews and conducted according to PRISMA guidelines; databases included MEDLINE and Embase, and all studies were quality assessed. Original studies (2005 to 2017) reporting follow-up of adults with THA in situ >5 years were included. Researchers extracted quantitative and qualitative data from each study. For eligibility, 4,137 studies were screened: 114 studies were included in the final analysis, representing 22 countries worldwide. Data extracted included study endpoint, patient detail, loss to follow-up, revisions, scores and radiographic analysis. Six themes were derived from inductive content analysis of text: support for long-term follow-up, subgroups requiring follow-up, effect of materials/techniques on THA survival, effect of design, indicators for revision, review process. Main findings-follow-up was specifically recommended to monitor change (eg asymptomatic loosening), when outcomes of joint construct are unknown, and for specific patient subgroups. Outcome scores alone are not enough, and radiographic review should be included. There were no studies directly evaluating the clinical effectiveness of the long-term follow-up of THA but expert opinions from a range of international authors advocated its use for defined subgroups to provide patient-centred care. In the absence of higher level evidence, these opinions, in conjunction with emerging outputs from the national joint registries, should be used to inform services for long-term follow-up of THA.

摘要

全髋关节置换术(THA)非常成功,但国家登记处显示,接受该手术的患者平均年龄有所降低,且年轻患者翻修风险更高。以往一直建议对THA进行长期随访,以识别无菌性失败的THA,尽量减少与广泛翻修相关的风险,但目前随访服务在减少。本研究进行了一项系统评价,以寻找髋关节置换术监测的临床或成本效益证据。该研究已在国际前瞻性系统评价注册库PROSPERO注册,并按照PRISMA指南进行;数据库包括MEDLINE和Embase,所有研究均进行了质量评估。纳入了2005年至2017年报告原位THA成人患者随访时间超过5年的原始研究。研究人员从每项研究中提取了定量和定性数据。为确定纳入资格,共筛选了4137项研究:最终分析纳入了114项研究,代表全球22个国家。提取的数据包括研究终点、患者详细信息、失访情况、翻修情况、评分及影像学分析。通过对文本的归纳性内容分析得出了六个主题:对长期随访的支持、需要随访的亚组、材料/技术对THA生存率的影响、设计的影响、翻修指标、评价过程。主要发现——特别建议进行随访以监测变化(如无症状性松动),当关节结构的结果未知时,以及针对特定患者亚组。仅靠结果评分是不够的,还应包括影像学检查。没有研究直接评估THA长期随访的临床效果,但一系列国际作者的专家意见主张对特定亚组使用长期随访,以提供以患者为中心的护理。在缺乏更高水平证据的情况下,这些意见应与国家关节登记处的新数据相结合,为THA长期随访服务提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff65/6613453/79cb494bcbf1/ORR-11-69-g0001.jpg

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