Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Australia.
Traumaplasty Melbourne, East Melbourne, Australia.
Clin Orthop Relat Res. 2024 Jan 1;482(1):98-112. doi: 10.1097/CORR.0000000000002737. Epub 2023 Jun 20.
Patient-reported outcome measures (PROMs) are a pragmatic and efficient means to evaluate the functional quality of arthroplasty beyond revision rates, which are used by most joint replacement registries to judge success. The relationship between these two measures of quality-revision rates and PROMs-is unknown, and not every procedure with a poor functional result is revised. It is logical-although still untested-that higher cumulative revision rates correlate inversely with PROMs for individual surgeons; more revisions are associated with lower PROM scores.
QUESTIONS/PURPOSES: We used data from a large national joint replacement registry to ask: (1) Does a surgeon's early THA cumulative percent revision (CPR) rate and (2) early TKA CPR rate correlate with the postoperative PROMs of patients undergoing primary THA and TKA, respectively, who have not undergone revision?
Elective primary THA and TKA procedures in patients with a primary diagnosis of osteoarthritis that were performed between August 2018 and December 2020 and registered in the Australian Orthopaedic Association National Joint Replacement Registry PROMs program were eligible. THAs and TKAs were eligible for inclusion in the primary analysis if 6-month postoperative PROMs were available, the operating surgeon was clearly identified, and the surgeon had performed at least 50 primary THAs or TKAs. Based on the inclusion criteria, 17,668 THAs were performed at eligible sites. We excluded 8878 procedures that were not matched to the PROMs program, leaving 8790 procedures. A further 790 were excluded because they were performed by unknown or ineligible surgeons or were revised, leaving 8000 procedures performed by 235 eligible surgeons, including 4256 (53%; 3744 cases of missing data) patients who had postoperative Oxford Hip Scores and 4242 (53%; 3758 cases of missing data) patients who had a postoperative EQ-VAS score recorded. Complete covariate data were available for 3939 procedures for the Oxford Hip Score and for 3941 procedures for the EQ-VAS. A total of 26,624 TKAs were performed at eligible sites. We excluded 12,685 procedures that were not matched to the PROMs program, leaving 13,939 procedures. A further 920 were excluded because they were performed by unknown or ineligible surgeons, or because they were revisions, leaving 13,019 procedures performed by 276 eligible surgeons, including 6730 (52%; 6289 cases of missing data) patients who had had postoperative Oxford Knee Scores and 6728 (52%; 6291 cases of missing data) patients who had a postoperative EQ-VAS score recorded. Complete covariate data were available for 6228 procedures for the Oxford Knee Score and for 6241 procedures for the EQ-VAS. The Spearman correlation between the operating surgeon's 2-year CPR and 6-month postoperative EQ-VAS Health and Oxford Hip or Oxford Knee Score was evaluated for THA and TKA procedures where a revision had not been performed. Associations between postoperative Oxford and EQ-VAS scores and a surgeon's 2-year CPR were estimated based on multivariate Tobit regressions and a cumulative link model with a probit link, adjusting for patient age, gender, ASA score, BMI category, preoperative PROMs, as well as surgical approach for THA. Missing data were accounted for using multiple imputation, with models assuming they were missing at random and a worst-case scenario.
Of the eligible THA procedures, postoperative Oxford Hip Score and surgeon 2-year CPR were correlated so weakly as to be clinically irrelevant (Spearman correlation ρ = -0.09; p < 0.001), and the correlation with postoperative EQ-VAS was close to zero (ρ = -0.02; p = 0.25). Of the eligible TKA procedures, postoperative Oxford Knee Score and EQ-VAS and surgeon 2-year CPR were correlated so weakly as to be clinically irrelevant (ρ = -0.04; p = 0.004 and ρ = 0.03; p = 0.006, respectively). All models accounting for missing data found the same result.
A surgeon's 2-year CPR did not exhibit a clinically relevant correlation with PROMs after THA or TKA, and all surgeons had similar postoperative Oxford scores. PROMs, revision rates, or both may be inaccurate or imperfect indicators of successful arthroplasty. Missing data may limit the findings of this study, although the results were consistent under a variety of different missing data scenarios. Innumerable factors contribute to arthroplasty results, including patient-related variables, differences in implant design, and the technical quality of the procedure. PROMs and revision rates may be analyzing two different facets of function after arthroplasty. Although surgeon variables are associated with revision rates, patient factors may exert a stronger influence on functional outcomes. Future research should identify variables that correlate with functional outcome. Additionally, given the gross level of function that Oxford scores record, outcome measures that can identify clinically meaningful functional differences are required. The use of Oxford scores in national arthroplasty registries may rightfully be questioned.
Level III, therapeutic study.
患者报告的结局测量(PROMs)是评估关节置换术除翻修率以外的功能质量的一种实用且高效的方法,大多数关节置换登记处都使用翻修率来判断手术的成功。这两种质量衡量标准(翻修率和 PROMs)之间的关系尚不清楚,而且并非每一个功能结果不佳的手术都会进行翻修。从逻辑上讲(尽管尚未经过验证),更高的累积翻修率与个别外科医生的 PROMs 呈负相关;更多的翻修与较低的 PROM 评分相关。
问题/目的:我们使用来自大型国家关节置换登记处的数据,询问:(1)外科医生的初次全髋关节置换术(THA)累积百分比翻修率(CPR)和(2)初次全膝关节置换术(TKA)CPR 是否与未进行翻修的初次 THA 和 TKA 患者的术后 PROMs 相关。
在 2018 年 8 月至 2020 年 12 月期间,在澳大利亚矫形协会国家关节置换登记处的 PROMs 项目下,对患有骨关节炎的患者进行的择期初次 THA 和 TKA 手术符合纳入标准。THA 和 TKA 符合主要分析的纳入标准,前提是术后 6 个月有 PROMs 数据,明确了手术医生的身份,并且外科医生至少进行了 50 例初次 THA 或 TKA。根据纳入标准,有 17668 例 THA 在符合条件的地点进行。我们排除了 8878 例未与 PROMs 项目匹配的手术,留下 8790 例手术。由于手术医生不明或不符合条件,或手术进行了翻修,进一步排除了 790 例,留下了 8000 例由 235 名符合条件的外科医生进行的手术,包括 4256 例(53%;3744 例缺失数据)术后牛津髋关节评分和 4242 例(53%;3758 例缺失数据)术后 EQ-VAS 评分记录的患者。术后牛津髋关节评分的完整协变量数据可用于 3939 例手术,EQ-VAS 的完整协变量数据可用于 3941 例手术。有 13939 例 THA 在符合条件的地点进行,我们排除了 12685 例未与 PROMs 项目匹配的手术,留下 13939 例。由于手术医生不明或不符合条件,或手术进行了翻修,进一步排除了 920 例,留下了 13019 例由 276 名符合条件的外科医生进行的手术,包括 6730 例(52%;6289 例缺失数据)术后牛津膝关节评分和 6728 例(52%;6291 例缺失数据)术后 EQ-VAS 评分记录的患者。术后牛津膝关节评分的完整协变量数据可用于 6228 例手术,EQ-VAS 的完整协变量数据可用于 6241 例手术。在未进行翻修的 THA 和 TKA 手术中,评估了手术医生 2 年 CPR 与术后 6 个月 EQ-VAS 健康和牛津髋关节或牛津膝关节评分之间的斯皮尔曼相关性。基于多元 Tobit 回归和具有概率单位链接的累积链接模型,调整了患者年龄、性别、ASA 评分、BMI 类别、术前 PROMs 以及手术入路等因素,估计了术后牛津和 EQ-VAS 评分与外科医生 2 年 CPR 之间的关联。缺失数据通过多重插补进行处理,模型假设它们是随机缺失的,并采用最坏情况假设。
在符合条件的初次 THA 手术中,术后牛津髋关节评分和外科医生 2 年 CPR 之间的相关性弱到几乎没有临床意义(Spearman 相关系数 ρ=-0.09;p<0.001),与术后 EQ-VAS 的相关性接近零(ρ=-0.02;p=0.25)。在符合条件的初次 TKA 手术中,术后牛津膝关节评分和 EQ-VAS 以及外科医生 2 年 CPR 之间的相关性弱到几乎没有临床意义(ρ=-0.04;p=0.004 和 ρ=-0.03;p=0.006)。所有考虑缺失数据的模型都得出了相同的结果。
外科医生的 2 年 CPR 与 THA 或 TKA 后的 PROMs 之间没有表现出具有临床意义的相关性,所有外科医生的术后牛津评分相似。PROMs、翻修率或两者都可能是不准确或不完善的成功关节置换术的指标。缺失数据可能会限制本研究的发现,尽管在各种不同的缺失数据情况下,结果都是一致的。无数因素共同影响着关节置换的结果,包括患者相关变量、植入物设计差异以及手术技术质量。PROMs 和翻修率可能在分析关节置换术后的两个不同功能方面。尽管外科医生的变量与翻修率相关,但患者因素可能对功能结果产生更强的影响。未来的研究应该确定与功能结果相关的变量。此外,鉴于牛津评分记录的功能水平,需要能够识别出具有临床意义的功能差异的功能结果测量方法。国家关节置换登记处使用牛津评分可能会受到质疑。
III 级,治疗性研究。