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产瘫性肩关节畸形与挛缩形成的发病机制——综述

The Pathogenesis of Glenohumeral Deformity and Contracture Formation in Obstetric Brachial Plexus Palsy-A Review.

作者信息

Olofsson Pontus N, Chu Alice, McGrath Aleksandra M

机构信息

Department of Hand and Plastic Surgery, Norrland's University Hospital, Umeå, Sweden.

Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.

出版信息

J Brachial Plex Peripher Nerve Inj. 2019 Jul 12;14(1):e24-e34. doi: 10.1055/s-0039-1692420. eCollection 2019 Jan.

Abstract

Contractures of the shoulder joint and glenohumeral joint dysplasia are well known complications to obstetrical brachial plexus palsy. Despite extensive description of these sequelae, the exact pathogenesis remains unknown. The prevailing theory to explain the contractures and glenohumeral joint dysplasia states that upper trunk injury leads to nonuniform muscle recovery and thus imbalance between internal and external rotators of the shoulder. More recently, another explanation has been proposed, hypothesizing that denervation leads to reduced growth of developing muscles and that reinnervation might suppress contracture formation. An understanding of the pathogenesis is desirable for development of effective prophylactic treatment. This article aims to describe the current state of knowledge regarding these important complications.

摘要

肩关节挛缩和肱骨头关节发育不良是产科臂丛神经麻痹的常见并发症。尽管对这些后遗症已有广泛描述,但其确切发病机制仍不清楚。解释挛缩和肱骨头关节发育不良的主流理论认为,上干损伤导致肌肉恢复不均匀,从而使肩部内旋肌和外旋肌之间失衡。最近,又有人提出了另一种解释,假设去神经支配会导致发育中的肌肉生长减缓,而再支配可能会抑制挛缩形成。了解发病机制有助于开发有效的预防性治疗方法。本文旨在描述关于这些重要并发症的当前知识状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6efd/6625958/b159c65e2316/10-1055-s-0039-1692420-i1800002rev-1.jpg

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