Department of Otorhinolaryngology, Akershus University Hospital, Lorenskog, Norway.
Department of Otorhinolaryngology, Akershus University Hospital, Lorenskog, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Rhinology. 2019 Dec 1;57(6):436-443. doi: 10.4193/Rhin19.178.
Nasal septoplasty is a common surgical procedure, but a significant number of patients report equal, or some even worsened, symptom load postoperatively. Rhinologists struggle to find objective tests that adequately reflects disease burden. This study aimed to evaluate the correlation between the PNIF measurement of the most obstructed side with patient reported outcomes.
Bilateral and unilateral PNIF measurements were performed before and after topical decongestion in 528 patients scheduled for surgery due to nasal obstruction. Subjective outcomes were measured using Nasal Obstruction VAS and SNOT-22 with subdomains. Correlations between subjective and objective measurements were calculated and further explored using multivariate regression analyses.
Significant negative correlations between PNIF and patient reported outcomes were found. Both bilateral and minimal unilateral PNIF correlations with NO-VAS were equal and stronger than correlations with SNOT-22 including subdomains concerning problems with nasal obstruction. Minimal unilateral PNIF did not show statistically significant gender difference. Topical decongestion decreased statistical correlations.
The minimal unilateral PNIF shows a statistically significant but weak negative correlation with preoperative patient reported nasal obstruction, and values do not differ between genders. Clinical evaluation of patients presenting complaints of nasal obstruction could be supported by minimal unilateral PNIF.
鼻中隔成形术是一种常见的手术，但相当数量的患者报告术后症状负荷相等，甚至有些患者症状加重。鼻科医生努力寻找能充分反映疾病负担的客观测试。本研究旨在评估最阻塞侧的 PNIF 测量值与患者报告的结果之间的相关性。
在 528 名因鼻塞而计划手术的患者中，进行了双侧和单侧 PNIF 测量，在局部去充血前后进行。使用鼻腔阻塞视觉模拟评分（Nasal Obstruction VAS）和 SNOT-22 及其子域来测量主观结果。计算了主观和客观测量之间的相关性，并使用多元回归分析进一步探讨了这些相关性。
发现 PNIF 与患者报告的结果之间存在显著的负相关。双侧和最小单侧 PNIF 与 NO-VAS 的相关性相等且强于与 SNOT-22 的相关性，包括与鼻腔阻塞相关问题的子域。最小单侧 PNIF 没有表现出统计学上显著的性别差异。局部去充血降低了统计相关性。
最小单侧 PNIF 与术前患者报告的鼻腔阻塞呈统计学显著但较弱的负相关，且性别之间无差异。有鼻腔阻塞症状的患者的临床评估可以通过最小单侧 PNIF 得到支持。
