Lee S I, Kirby D
Department of Neurology, University of Virginia School of Medicine, Charlottesville 22908.
Epilepsia. 1988 May-Jun;29(3):262-7. doi: 10.1111/j.1528-1157.1988.tb03716.x.
In seven children, 5-11 years old, who presented with spells of staring or unresponsiveness, hyperventilation reproduced clinical spells that were accompanied on the EEG by generalized, rhythmic, delta activity. The discharges were usually of abrupt onset, extremely high amplitude, recurrent, and prolonged. One spontaneous staring spell, not provoked by hyperventilation, was also accompanied by generalized rhythmic delta activity. All patients had improvement or complete control of their spells and abolition of the EEG changes with ethosuximide or valproate. Delta activity during hyperventilation in children may not always be benign and may be associated with clinical absence seizures.
在7名5至11岁出现凝视发作或无反应发作的儿童中,过度换气诱发了临床发作,脑电图显示伴有广泛性、节律性δ活动。放电通常起病突然、振幅极高、反复出现且持续时间长。1次未被过度换气诱发的自发凝视发作也伴有广泛性节律性δ活动。所有患者使用乙琥胺或丙戊酸盐后发作得到改善或完全控制,脑电图变化消失。儿童过度换气时的δ活动不一定总是良性的,可能与临床失神发作有关。