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[耐多药肺外结核病：约7例]

[Multidrug-resistant extrapulmonary tuberculosis: about 7 cases].

作者信息

Haddaoui Hanane, Mrabet Fatima Zahra, Aharmim Mohammed, Bourkadi Jamal-Eddine

机构信息

Service de Pneumo-Phtisiologie, Hôpital Moulay Youssef, CHU Rabat, Akkari, Faculté de Médecine et de Pharmacie de Rabat, Maroc.

出版信息

Pan Afr Med J. 2019 Apr 23;32:196. doi: 10.11604/pamj.2019.32.196.17995. eCollection 2019.

DOI:10.11604/pamj.2019.32.196.17995
PMID:31312308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6620082/
Abstract

Multidrug-resistant tuberculosis is a major challenge for the World Health Organization. Its growing incidence and the diagnostic and therapeutic difficulties make it a public health problem especially in the developing countries. We report two cases of extrapulmonary drug-resistant tuberculosis (nodal and osteo-articular) and five cases of pulmonary tuberculosis and extra-pulmonary tuberculosis (pleural, nodal, anal and neuro-meningeal) in hospitalized patients at the Hopital Moulay Youssef in Rabat. This study reports the issue of drug-resistant TB and highlights the role of genotypic tests in the diagnosis of extrapulmonary tuberculosis.

摘要

耐多药结核病是世界卫生组织面临的一项重大挑战。其发病率不断上升以及诊断和治疗方面的困难使其成为一个公共卫生问题，在发展中国家尤为如此。我们报告了拉巴特穆莱·优素福医院住院患者中两例肺外耐药结核病（淋巴结和骨关节）病例以及五例肺结核和肺外结核病（胸膜、淋巴结、肛门和神经脑膜）病例。本研究报告了耐多药结核病问题，并强调了基因检测在肺外结核病诊断中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/40f2425707ad/PAMJ-32-196-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/0c16725e28f7/PAMJ-32-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/4fc97fdda240/PAMJ-32-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/71e77272f649/PAMJ-32-196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/aecd201daa6d/PAMJ-32-196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/37404fc9ccce/PAMJ-32-196-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/8f6a71b6837c/PAMJ-32-196-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/40f2425707ad/PAMJ-32-196-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/0c16725e28f7/PAMJ-32-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/4fc97fdda240/PAMJ-32-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/71e77272f649/PAMJ-32-196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/aecd201daa6d/PAMJ-32-196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/37404fc9ccce/PAMJ-32-196-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/8f6a71b6837c/PAMJ-32-196-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cc5/6620082/40f2425707ad/PAMJ-32-196-g007.jpg

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本文引用的文献

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Treatment outcome of patients having extensively drug-resistant tuberculosis in Gujarat, India.印度古吉拉特邦广泛耐药结核病患者的治疗结果。
Int J Mycobacteriol. 2017 Jul-Sep;6(3):289-295. doi: 10.4103/ijmy.ijmy_59_17.
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免疫功能正常患者发生耐多药结核性咽后脓肿：一例报告。
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[Management of multidrug-resistant tuberculosis].[耐多药结核病的管理]
Rev Pneumol Clin. 2015 Apr-Jun;71(2-3):130-9. doi: 10.1016/j.pneumo.2014.05.001. Epub 2014 Aug 19.
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Primary disseminated extrapulmonary multidrug resistant tuberculosis.原发性播散性肺外多药耐药结核病
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[Bacteriological tests for tuberculosis].[结核病的细菌学检测]
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HIV coinfection in multidrug- and extensively drug-resistant tuberculosis results in high early mortality.HIV 合并感染多重和广泛耐药结核病会导致早期高死亡率。
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