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单取代磷酰胍三脱氧核糖核苷酸非对映异构体的分离及性质分析数据。

Data for isolation and properties analysis of diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide.

作者信息

Lomzov Alexander A, Kupryushkin Maxim S, Shernyukov Andrey V, Nekrasov Mikhail D, Dovydenko Ilya S, Stetsenko Dmitry A, Pyshnyi Dmitrii V

机构信息

Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8 Lavrentiev Avenue, Novosibirsk, 630090, Russia.

Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia.

出版信息

Data Brief. 2019 Jun 20;25:104148. doi: 10.1016/j.dib.2019.104148. eCollection 2019 Aug.

DOI:10.1016/j.dib.2019.104148
PMID:31312699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6609727/
Abstract

This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom phosphodiesterase and structural analysis by 1D and 2D NMR spectroscopy and restrained molecular dynamics analysis. The data can be used for preparation, analysis, application of phosphoryl guanidine oligonucleotide and for development of new nucleic acids derivatives. This data article is associated with the manuscript titled "Diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide: isolation and properties" [1].

摘要

本文介绍了单取代磷酰胍三脱氧核糖核苷酸d(TpCp*A)非对映异构体性质的新数据[1,2]。这些数据包括关于分离、鉴定、用蛇毒磷酸二酯酶处理以及通过一维和二维核磁共振光谱进行结构分析和受限分子动力学分析的信息。这些数据可用于磷酰胍寡核苷酸的制备、分析、应用以及新型核酸衍生物的开发。本数据文章与题为“单取代磷酰胍三脱氧核糖核苷酸的非对映异构体：分离与性质”的手稿相关[1]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/75d06bd7bc1c/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/4dd1d15ca0bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/3b148077af8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/90dd431ae2f5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/a35f7aedfc85/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/38b43dd39a6a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/9e222f0a5a5d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/32d8cc078b99/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/76e77f82f21a/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/66511cc0ea57/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/f0c856a5165e/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/1059ebd7ff89/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/7279c7a14ec8/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/772c3564445a/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/75d06bd7bc1c/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/4dd1d15ca0bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/3b148077af8a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/90dd431ae2f5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/a35f7aedfc85/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/38b43dd39a6a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/9e222f0a5a5d/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/32d8cc078b99/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/76e77f82f21a/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/66511cc0ea57/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/f0c856a5165e/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/1059ebd7ff89/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/7279c7a14ec8/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/772c3564445a/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaa2/6609727/75d06bd7bc1c/gr11.jpg

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