前列腺原始神经外胚层肿瘤以背痛和截瘫为首发症状：病例报告及文献复习。
Primitive Neuroectodermal Tumor of the Prostate with Notalgia and Paraplegia as the Initial Symptoms: A Case Report and Literature Review.
机构信息
Department of Radiation Oncology, Fourth Affiliated Hospital of China Medical University, Shenyang, PR China.
Department of Radiation Oncology, General Hospital of Northern Military Area, Shenyang, PR China.
出版信息
J Adolesc Young Adult Oncol. 2019 Dec;8(6):697-701. doi: 10.1089/jayao.2019.0052. Epub 2019 Jul 16.
Primitive neuroectodermal tumor (PNET) is a rare and highly malignant neoplasm composed of small round cells, which frequently occurs in children and adolescents. PNET originating from the prostate is even rarer. We report a case of PNET of the prostate with notalgia and paraplegia as the initial symptoms. Positron emission tomography-computed tomography scanning showed hypodense and hypermetabolism on the prostate; subsequently, we ascertained the diagnosis by transrectal ultrasound-guided biopsy. The patient underwent local vertebral radiotherapy combined with five courses of systematic chemotherapy. Disease progressed after 11 months, and the overall survival was 17 months.
原始神经外胚层肿瘤（PNET）是一种罕见的高度恶性肿瘤，由小圆细胞组成，常发生于儿童和青少年。原发于前列腺的 PNET 更为罕见。我们报告了一例以背痛和截瘫为首发症状的前列腺 PNET。正电子发射断层扫描-计算机断层扫描显示前列腺呈低密 度和高代谢；随后，我们通过经直肠超声引导下活检确定了诊断。患者接受了局部脊柱放疗联合五轮系统化疗。11 个月后疾病进展，总生存期为 17 个月。
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