Vieira Luana Gabriela Dalla Rosa, Safanelli Juliana, Araujo Tainá de, Schuch Helen Aparecida, Kuhlhoff Maria Helena Ribeiro, Nagel Vivian, Conforto Adriana Bastos, Silva Gisele Sampaio, Mazin Suleimy, Cabral Norberto Luiz
Universidade da Região de Joinville, Joinville, SC, Brasil.
Registro de AVC de Joinville, Joinville, SC, Brasil.
Arq Neuropsiquiatr. 2019 Jul 15;77(6):393-403. doi: 10.1590/0004-282X20190056.
Few studies from low- and middle-income countries have assessed stroke and cerebral reperfusion costs from the private sector. To measure the in-hospital costs of ischemic stroke (IS), with and without cerebral reperfusion, primary intracerebral hemorrhage (PIH), subarachnoid hemorrhage (SAH) and transient ischemic attacks (TIA) in two private hospitals in Joinville, Brazil.
Prospective disease-cost study. All medical and nonmedical costs for patients admitted with any stroke type or TIA were consecutively determined in 2016-17. All costs were adjusted to the gross domestic product deflator index and purchasing power parity.
We included 173 patients. The median cost per patient was US$3,827 (IQR: 2,800-8,664) for the 131 IS patients; US$2,315 (IQR: 1,692-2,959) for the 27 TIA patients; US$16,442 (IQR: 5,108-33,355) for the 11 PIH patients and US$28,928 (IQR: 12,424-48,037) for the four SAH patients (p < 0.00001). For the six IS patients who underwent intravenous thrombolysis, the median cost per patient was US$11,463 (IQR: 8,931-14,291), and for the four IS patients who underwent intra-arterial thrombectomy, the median cost per patient was US$35,092 (IQR: 31,833-37,626; p < 0.0001). A direct correlation was found between cost and length of stay (r = 0.67, p < 0.001).
Stroke is a costly disease. In the private sector, the costs of cerebral reperfusion for IS treatment were three-to-ten times higher than for usual treatments. Therefore, cost-effectiveness studies are urgently needed in low- and middle-income countries.
来自低收入和中等收入国家的研究很少评估私立部门的中风和脑再灌注成本。为了衡量巴西茹安维尔市两家私立医院中缺血性中风(IS)伴或不伴脑再灌注、原发性脑出血(PIH)、蛛网膜下腔出血(SAH)和短暂性脑缺血发作(TIA)的住院成本。
前瞻性疾病成本研究。2016 - 17年连续确定了所有因任何中风类型或TIA入院患者的所有医疗和非医疗成本。所有成本均根据国内生产总值平减指数和购买力平价进行了调整。
我们纳入了173名患者。131名IS患者的人均成本中位数为3827美元(四分位间距:2800 - 8664美元);27名TIA患者为2315美元(四分位间距:1692 - 2959美元);11名PIH患者为16442美元(四分位间距:5108 - 33355美元);4名SAH患者为28928美元(四分位间距:12424 - 48037美元)(p < 0.00001)。6名接受静脉溶栓的IS患者人均成本中位数为11463美元(四分位间距:8931 - 14291美元),4名接受动脉内血栓切除术的IS患者人均成本中位数为35092美元(四分位间距:31833 - 37626美元;p < 0.0001)。发现成本与住院时间之间存在直接相关性(r = 0.67,p < 0.001)。
中风是一种成本高昂的疾病。在私立部门,IS治疗的脑再灌注成本比常规治疗高出三到十倍。因此,低收入和中等收入国家迫切需要进行成本效益研究。