Lucassen Eliane A, la Chapelle Claire F, Krouwel Esmee, Groeneveld Marc
Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Department of Internal Medicine, Haaglanden Medical Center, The Hague, The Netherlands.
BMJ Case Rep. 2019 Jul 16;12(7):e229318. doi: 10.1136/bcr-2019-229318.
Pelvic organ prolapse (POP), the transvaginal descent of pelvic organs, can cause mild hydronephrosis but rarely leads to a deterioration in kidney function. We present a case of severe uterovaginal prolapse that caused bilateral ureteral obstruction and led to renal failure and urinary tract infection. During outpatient follow-up, kidney function had already been deteriorating, but POP was not recognised as a causal factor. A longer duration of ureteral obstruction can lead to irreversible kidney damage, and therefore, timely recognition and intervention is of essence. Even in complex cases with various causative factors for kidney injury, the presence of severe POP and kidney injury should prompt the clinician to exclude this cause.
盆腔器官脱垂（POP）是指盆腔器官经阴道下移，可导致轻度肾积水，但很少导致肾功能恶化。我们报告一例严重子宫阴道脱垂病例，该病例导致双侧输尿管梗阻，进而引发肾衰竭和尿路感染。在门诊随访期间，肾功能已经在恶化，但POP未被识别为病因。输尿管梗阻时间延长可导致不可逆的肾损伤，因此，及时识别和干预至关重要。即使在存在多种肾损伤病因的复杂病例中，严重POP和肾损伤的存在也应促使临床医生排除这一病因。
