染色质重塑机器在癌症中的多样组成和功能。
Diverse compositions and functions of chromatin remodeling machines in cancer.
机构信息
Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Email:
出版信息
Sci Transl Med. 2019 Jul 17;11(501). doi: 10.1126/scitranslmed.aay1018.
Abstract
Human cancer genetics power biochemical and functional interrogation of chromatin remodeling complexes, informing therapeutic opportunities.
摘要
人类癌症遗传学为染色质重塑复合物的生化和功能研究提供了动力，为治疗提供了新的机会。
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