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胰十二指肠切除术后19年发生破裂性化脓性肝脓肿并气腹

Ruptured Pyogenic Liver Abscess with Pneumoperitoneum 19 Years After Pancreatoduodenectomy.

作者信息

Shiryajev Yuri N, Ryllo Andrey G, Grechukhin Sergey N, Karpenko Maria O, Busheva Anna I, Koronnova Elena N, Glebova Anna V, Kokhanenko Nikolay Y

机构信息

Fourth Department of Surgery, Saint Petersburg City Hospital #15, Saint Petersburg, Russian Federation.

Department of Hospital Surgery #2, I.P. Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russian Federation.

出版信息

Am J Case Rep. 2019 Jul 18;20:1039-1045. doi: 10.12659/AJCR.916755.

Abstract

BACKGROUND Rupture of a pyogenic liver abscess is rare but serious complication. In patients after pancreatoduodenectomy, there are some conditions causing the development of liver abscesses (e.g., chronic reflux-cholangitis, efferent jejunal loop stasis, stenosis of the biliary anastomosis, and pancreatogenic diabetes). However, the number of published cases of liver abscess after pancreatoduodenectomy is small. CASE REPORT A 42-year-old male was admitted with severe abdominal pain, fever, and jaundice. Nineteen years previously, he had undergone pancreatoduodenectomy and cholecystectomy for chronic pancreatitis with obstructive jaundice. Two years later, diabetes mellitus was diagnosed, with subsequent insulin treatment. At admission, symptoms of peritonitis were present. Plain abdominal radiography showed free gas under the right hemidiaphragm and heterogeneous liver shade with small gas-fluid levels. The rupture of a liver abscess was suspected. Laparotomy with adhesiolysis, debridement of the liver abscess cavity, and abdominal drainage were performed. The postoperative period was complicated by sepsis, right lower lobe pneumonia, and two-sided pleural effusions, on the background of insulin-dependent diabetes and malnutrition. The patient was discharged on the 40th day and the subdiaphragmatic drains were removed on the 114th day. Sixteen months after surgery, the patient's condition was satisfactory. Magnetic resonance imaging and echography showed the absence of biliary hypertension. The liver tissue had healed completely. CONCLUSIONS A unique case of ruptured liver abscess after pancreatoduodenectomy is presented. To the best of our knowledge, this is the first published case with such a long time interval (19 years) between pancreatoduodenectomy and the formation of a pyogenic liver abscess.

摘要

背景 化脓性肝脓肿破裂是一种罕见但严重的并发症。在胰十二指肠切除术后的患者中,存在一些导致肝脓肿形成的情况(如慢性反流性胆管炎、空肠输出袢淤滞、胆肠吻合口狭窄和胰源性糖尿病)。然而,胰十二指肠切除术后肝脓肿的已发表病例数量较少。病例报告 一名42岁男性因严重腹痛、发热和黄疸入院。19年前,他因慢性胰腺炎伴梗阻性黄疸接受了胰十二指肠切除术和胆囊切除术。两年后,被诊断为糖尿病,随后接受胰岛素治疗。入院时,存在腹膜炎症状。腹部平片显示右膈下有游离气体,肝脏影像不均匀,有小的气液平面。怀疑是肝脓肿破裂。进行了剖腹探查,包括粘连松解、肝脓肿腔清创和腹腔引流。术后出现败血症、右下叶肺炎和双侧胸腔积液等并发症,患者存在胰岛素依赖型糖尿病和营养不良。患者于第40天出院,膈下引流管于第114天拔除。术后16个月,患者情况良好。磁共振成像和超声检查显示无胆道高压。肝组织已完全愈合。结论 本文报道了一例胰十二指肠切除术后肝脓肿破裂的独特病例。据我们所知,这是第一例胰十二指肠切除术与化脓性肝脓肿形成间隔时间长达19年的已发表病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/920a/6659458/c597d95909b7/amjcaserep-20-1039-g001.jpg

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