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重度创伤性脑损伤患儿的颅内压监测:一项回顾性研究

Intracranial Pressure Monitoring in Children with Severe Traumatic Brain Injury: A Retrospective Study.

作者信息

Banik Sujoy, Rath Girija P, Lamsal Ritesh, Sinha Sumit, Bithal Parmod K

机构信息

Department of Anesthesia and Perioperative Medicine, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Department of Neuroanaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), New Delhi, India.

出版信息

J Pediatr Neurosci. 2019 Jan-Mar;14(1):7-15. doi: 10.4103/jpn.JPN_18_19.

Abstract

INTRODUCTION

There is a paucity of literature on intracranial pressure (ICP) monitoring in children. The aim of this study was to ascertain whether ICP monitoring is useful in children with severe traumatic brain injury (TBI).

MATERIALS AND METHODS

Medical records of children between 1 and 12 years, admitted to neurocritical care unit with severe TBI in 2 years, were reviewed. The children were divided into two groups: study group (ICP monitored) and control group (ICP not monitored). Admission demographics, vital parameters, and computed tomographic scan findings were recorded. In the study group, date of ICP catheter insertion/removal with ICP values and treatment carried out for increased ICP were noted. Data on tracheostomy, duration of mechanical ventilation, hospital stay, and outcome at discharge were noted.

RESULTS

Demographic variables were comparable between the two groups. When adjusted for death, no significant difference was observed between the study and the control groups in median duration of mechanical ventilation: 35 days (95% confidence interval [CI]: 12-73) versus 55 days (95% CI: 29-55) ( = 0.96), hospital stay: 36 days (95% CI: 12-73) versus 58 days (95% CI: 29-58) ( = 0.96), and time to tracheostomy: 6 days (95% CI: 5-8) versus 5 days (95% CI: 4-7) ( = 0.49). Mortality rates, incidence of cranial surgeries, and outcome at discharge were also comparable.

CONCLUSION

ICP monitoring did not reduce the incidence of death, cranial surgeries, duration of mechanical ventilation, hospital stay, or improve the outcome at discharge in children with severe TBI.

摘要

引言

关于儿童颅内压(ICP)监测的文献较少。本研究的目的是确定ICP监测对重度创伤性脑损伤(TBI)患儿是否有用。

材料与方法

回顾了2年内入住神经重症监护病房的1至12岁重度TBI患儿的病历。将患儿分为两组:研究组(进行ICP监测)和对照组(未进行ICP监测)。记录入院时的人口统计学数据、生命体征参数和计算机断层扫描结果。在研究组中,记录ICP导管插入/拔除日期、ICP值以及针对ICP升高所采取的治疗措施。记录气管切开术、机械通气时间、住院时间和出院结局的数据。

结果

两组的人口统计学变量具有可比性。在对死亡因素进行校正后,研究组和对照组在机械通气中位时间方面无显著差异:35天(95%置信区间[CI]:12 - 73)对55天(95%CI:29 - 55)(P = 0.96);住院时间方面:36天(95%CI:12 - 73)对58天(95%CI:29 - 58)(P = 0.96);气管切开时间方面:6天(95%CI:5 - 8)对5天(95%CI:4 - 7)(P = 0.49)。死亡率、颅骨手术发生率和出院结局也具有可比性。

结论

ICP监测并未降低重度TBI患儿的死亡率、颅骨手术发生率、机械通气时间、住院时间,也未改善出院结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b57/6601117/529359a9b7e7/JPN-14-7-g001.jpg

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