D - 二聚体水平与计算机断层扫描肺动脉造影显示的肺栓塞的存在及严重程度的相关性
Correlation of D-Dimer Level with the Presence and Severity of Pulmonary Embolism on Computed Tomography Pulmonary Angiography.
作者信息
Rawat Narendra, Mathur Navgeet, Rawat Kiran, Mathur Medha, Tinna Rajat, Kakkar Rahul, Didel Loonaram
机构信息
Department of General Medicine,Dr. S.N. Medical College, Jodhpur, Rajasthan.
Department of General Medicine, Pacific Institute of Medical Sciences, Udaipur, Rajasthan.;* Corresponding Author.
出版信息
J Assoc Physicians India. 2018 Oct;66(10):40-41.
INTRODUCTION
Early diagnosis of pulmonary embolism can reduce morbidity and motility. D-dimer is well known parameter having high negative prediction value. This study focused on role of D-dimer in early prediction of presence and severity of pulmonary embolism.
MATERIAL AND METHODS
Thirty patients with clinical suspicion of pulmonary embolism along with high D-dimer value were included in this study. All selected patients underwent computed tomography pulmonary angiography assessment. D- dimer value was correlated with presence and proximity of pulmonary embolism.
RESULTS
Out of thirty selected patients 50% had pulmonary embolism on computed tomography pulmonary angiography assessment. D-dimer value correlated well with presence and proximity of pulmonary embolism.
CONCLUSION
D-dimer value more than 4000 ng/ml had high positive prediction value (79%) in suspected clinical cases. Value more than 8000 ng/ml further improve value to nearly 100% in suspected cases.
引言
肺栓塞的早期诊断可降低发病率和死亡率。D-二聚体是一个众所周知的参数，具有较高的阴性预测价值。本研究聚焦于D-二聚体在早期预测肺栓塞的存在及严重程度方面的作用。
材料与方法
本研究纳入了30例临床怀疑肺栓塞且D-二聚体值较高的患者。所有入选患者均接受了计算机断层扫描肺动脉造影评估。D-二聚体值与肺栓塞的存在及程度相关。
结果
在30例入选患者中，50%在计算机断层扫描肺动脉造影评估中存在肺栓塞。D-二聚体值与肺栓塞的存在及程度相关性良好。
结论
在疑似临床病例中，D-二聚体值超过4000 ng/ml具有较高的阳性预测价值（79%）。在疑似病例中，超过8000 ng/ml的值可将预测价值进一步提高至近100%。
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