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[生长激素释放因子和前列腺素E2对灌流大鼠垂体前叶细胞系统中生长激素释放的控制]

[Control of growth hormone release by growth hormone-releasing factor and prostaglandin E2 in a system of perfused rat anterior pituitary cells].

作者信息

Fafeur V, Tiberghien C, Haour F, Dray F

机构信息

INSERM U.207-URIA, Institut Pasteur, Paris.

出版信息

Reprod Nutr Dev (1980). 1988;28(2A):229-31.

PMID:3131855
Abstract

Using superfused rat pituitary cells we showed that the growth hormone-releasing factor (GRF) and prostaglandin E2 (PGE2) increased growth hormone (GH) secretion in a similar manner in terms of kinetics and amplitude of responses. Moreover, our data suggest that they stimulate GH secretion mainly by cAMP-dependent mechanisms.

摘要

利用体外灌流的大鼠垂体细胞,我们发现,就反应的动力学和幅度而言,生长激素释放因子(GRF)和前列腺素E2(PGE2)以相似的方式增加生长激素(GH)的分泌。此外,我们的数据表明,它们主要通过依赖环磷酸腺苷(cAMP)的机制刺激GH分泌。

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1
[Control of growth hormone release by growth hormone-releasing factor and prostaglandin E2 in a system of perfused rat anterior pituitary cells].[生长激素释放因子和前列腺素E2对灌流大鼠垂体前叶细胞系统中生长激素释放的控制]
Reprod Nutr Dev (1980). 1988;28(2A):229-31.
2
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