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酷似主动脉瘤的胸腺瘤:时刻准备应对意外情况。

Thymoma mimicking an aortic aneurysm: always expect the unexpected.

作者信息

Michaux Dario, Berzenji Lawek, Keulen Lotte, Rodrigus Inez

机构信息

Thoracic and Vascular Surgery, University Hospital Antwerp, Edegem, Antwerpen, Belgium.

Pathology, University Hospital Antwerp, Edegem, Antwerpen, Belgium.

出版信息

BMJ Case Rep. 2019 Jul 17;12(7):e230073. doi: 10.1136/bcr-2019-230073.

DOI:10.1136/bcr-2019-230073
PMID:31320375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6663207/
Abstract

Thymic epithelial tumours (TETs) are rare lesions that represent less than 1% of all malignancies in adults. Presentation occurs in three ways: asymptomatic, with local thoracic symptoms or with paraneoplastic symptoms. Heterotopic ossifications are rare histological features in neoplasms and non-neoplastic lesions. Here, we present a 49-year-old male patient with a thymoma type B2 mimicking an aortic aneurysm. Alongside the thymoma, a cholesterol granuloma with unusual ossification features was found as well. This clinical presentation and pathological diagnosis are unusual findings.

摘要

胸腺上皮肿瘤(TETs)是罕见病变,在成人所有恶性肿瘤中占比不到1%。其临床表现有三种方式:无症状、有局部胸部症状或有副肿瘤症状。异位骨化是肿瘤和非肿瘤性病变中罕见的组织学特征。在此,我们报告一名49岁男性患者,其B2型胸腺瘤酷似主动脉瘤。除胸腺瘤外,还发现了一个具有异常骨化特征的胆固醇肉芽肿。这种临床表现和病理诊断均为不寻常的发现。

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Thymoma mimicking an aortic aneurysm: always expect the unexpected.酷似主动脉瘤的胸腺瘤:时刻准备应对意外情况。
BMJ Case Rep. 2019 Jul 17;12(7):e230073. doi: 10.1136/bcr-2019-230073.
2
Best cases from the AFIP: thymoma.武装部队病理研究所的最佳病例:胸腺瘤。
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Thymoma arising in the wall of a thymic cyst.起源于胸腺囊肿壁的胸腺瘤。
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A ring calcified benign thymoma in a patient with asbestos exposure.石棉暴露患者的环状钙化良性胸腺瘤。
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[Malignant thymoma with myasthenia gravis and hepatic metastasis. Report of a case and review of the literature].[恶性胸腺瘤伴重症肌无力及肝转移。1例报告并文献复习]
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Pure red cell aplasia associated with a thymoma.与胸腺瘤相关的纯红细胞再生障碍。
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本文引用的文献

1
Sclerosing thymoma: A rare case report and brief review of literature.硬化性胸腺瘤:一例罕见病例报告及文献简要综述
Medicine (Baltimore). 2018 Apr;97(16):e0520. doi: 10.1097/MD.0000000000010520.
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Cholesterol granuloma of the maxilla.上颌骨胆固醇肉芽肿
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3
Pathophysiology and immunological profile of myasthenia gravis and its subgroups.重症肌无力及其亚组的病理生理学和免疫学特征。
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IASLC/ITMIG Staging System and Lymph Node Map for Thymic Epithelial Neoplasms.国际肺癌研究协会/国际胸腺恶性肿瘤研究组胸腺上皮性肿瘤分期系统及淋巴结图谱
Radiographics. 2017 May-Jun;37(3):758-776. doi: 10.1148/rg.2017160096.
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Early Rule-Out and Rule-In Strategies for Myocardial Infarction.心肌梗死的早期排除和确诊策略
Clin Chem. 2017 Jan;63(1):129-139. doi: 10.1373/clinchem.2016.254730. Epub 2016 Oct 10.
6
Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I.利用心电图和基线高敏肌钙蛋白I即时排除急性心肌梗死
Clin Chem. 2017 Jan;63(1):394-402. doi: 10.1373/clinchem.2016.262659. Epub 2016 Nov 30.
7
Cholesterol granuloma of the anterior mediastinum.前纵隔胆固醇肉芽肿
Thorax. 2017 Jul;72(7):671-672. doi: 10.1136/thoraxjnl-2016-209481. Epub 2016 Oct 31.
8
Comparison of the Masaoka-Koga staging and the International Association for the Study of Lung Cancer/the International Thymic Malignancies Interest Group proposal for the TNM staging systems based on the Chinese Alliance for Research in Thymomas retrospective database.基于中国胸腺瘤研究联盟回顾性数据库,比较Masaoka-Koga分期与国际肺癌研究协会/国际胸腺恶性肿瘤兴趣小组提出的TNM分期系统。
J Thorac Dis. 2016 Apr;8(4):727-37. doi: 10.21037/jtd.2016.03.22.
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Thymoma and thymic carcinomas.胸腺瘤和胸腺癌。
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10
Thymic epithelial tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.胸腺上皮肿瘤:ESMO诊断、治疗及随访临床实践指南
Ann Oncol. 2015 Sep;26 Suppl 5:v40-55. doi: 10.1093/annonc/mdv277.