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来自法属圭亚那的临床分离株溃疡分枝杆菌CSURP7741的全基因组序列

Whole-Genome Sequence of Mycobacterium ulcerans CSURP7741, a French Guianan Clinical Isolate.

作者信息

Saad Jamal, Combe Marine, Hammoudi Nassim, Couppié Pierre, Blaizot Romain, Jedir Farah, Gozlan Rodolphe Elie, Drancourt Michel, Bouam Amar

机构信息

IHU Méditerranée Infection, Marseille, France.

Aix-Marseille-University, IRD, MEPHI, IHU Méditerranée Infection, Marseille, France.

出版信息

Microbiol Resour Announc. 2019 Jul 18;8(29):e00215-19. doi: 10.1128/MRA.00215-19.

DOI:10.1128/MRA.00215-19
PMID:31320424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6639603/
Abstract

Combined Nanopore and Illumina whole-genome sequencing of a French Guianan (Buruli ulcer agent) clinical isolate yielded a 5.12-Mbp genome with a 65.5% GC content, 5,215 protein-coding genes, and 51 predicted RNA genes. This publicly available whole-genome sequence from a strain isolated in South America is closely related to subsp. .

摘要

对来自法属圭亚那的一株(布鲁里溃疡病原体)临床分离株进行纳米孔测序与Illumina全基因组测序相结合,得到了一个512万个碱基对的基因组,其GC含量为65.5%,有5215个蛋白质编码基因和51个预测的RNA基因。这一来自在南美洲分离出的菌株的公开全基因组序列与亚种密切相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1549/6639603/258ce2af3e93/MRA.00215-19-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1549/6639603/258ce2af3e93/MRA.00215-19-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1549/6639603/258ce2af3e93/MRA.00215-19-f0001.jpg

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本文引用的文献

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Buruli Ulcer, a Prototype for Ecosystem-Related Infection, Caused by Mycobacterium ulcerans.布鲁里溃疡,一种由溃疡分枝杆菌引起的与生态系统相关感染的原型。
Clin Microbiol Rev. 2017 Dec 13;31(1). doi: 10.1128/CMR.00045-17. Print 2018 Jan.
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First detection of Mycobacterium ulcerans DNA in environmental samples from South America.在南美洲环境样本中首次检测到溃疡分枝杆菌DNA。
PLoS Negl Trop Dis. 2014 Jan 30;8(1):e2660. doi: 10.1371/journal.pntd.0002660. eCollection 2014.
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Complete genome sequence of the frog pathogen Mycobacterium ulcerans ecovar Liflandii.蛙类病原体溃疡分枝杆菌利福兰亚种的全基因组序列。
J Bacteriol. 2013 Feb;195(3):556-64. doi: 10.1128/JB.02132-12. Epub 2012 Nov 30.
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On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer.关于导致溃疡分枝杆菌病(Buruli 溃疡)的病原体,溃疡分枝杆菌的起源。
BMC Genomics. 2012 Jun 19;13:258. doi: 10.1186/1471-2164-13-258.
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