Brook I, Yocum P
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Ann Otol Rhinol Laryngol. 1988 May-Jun;97(3 Pt 1):243-6. doi: 10.1177/000348948809700306.
We studied the microbial flora of tonsils removed from 20 children who suffered from recurrent group A beta-hemolytic streptococcal (GABHS) tonsillitis and 20 who had tonsillar hypertrophy following recurrent non-GABHS tonsillitis. Similar polymicrobial aerobic and anaerobic flora were recovered from the cores of the tonsils in each group. beta-Lactamase-producing bacteria (BLPB) were recovered more often in the group with GABHS. This difference was due mostly to the lower incidence of beta-lactamase-producing strains of Branhamella catarrhalis and Bacteroides sp in hypertrophic tonsils following non-GABHS tonsillitis. beta-Lactamase-producing Staphylococcus aureus was found with equal frequency in both groups. These findings demonstrate that although BLPB are recovered more often in recurrently inflamed tonsils following GABHS infection, BLPB also can be found in hypertrophic tonsils following non-GABHS tonsillitis.
我们研究了从20名患有复发性A组β溶血性链球菌（GABHS）扁桃体炎的儿童以及20名在复发性非GABHS扁桃体炎后出现扁桃体肥大的儿童身上切除的扁桃体的微生物菌群。在每组扁桃体的核心部位均发现了相似的需氧和厌氧混合微生物菌群。在GABHS组中，产β-内酰胺酶细菌（BLPB）的检出率更高。这种差异主要是由于在非GABHS扁桃体炎后肥大的扁桃体中，卡他布兰汉菌和拟杆菌属中产β-内酰胺酶菌株的发生率较低。两组中产β-内酰胺酶金黄色葡萄球菌的检出频率相同。这些发现表明，虽然在GABHS感染后反复发炎的扁桃体中BLPB的检出率更高，但在非GABHS扁桃体炎后的肥大扁桃体中也能发现BLPB。
