Loomis Meagan, Kosinski Tracy, Wucherer Stacy
Aurora Health Care, Milwaukee, WI, USA.
Concordia University Wisconsin School of Pharmacy, Mequon, USA.
Hosp Pharm. 2019 Aug;54(4):259-265. doi: 10.1177/0018578718788841. Epub 2018 Jul 18.
The purpose of the study is to develop and implement a standardized sterile compounding training program in a multihospital system that incorporates sterile compounding best practice recommendations and ensures compliance with United States Pharmacopeia (USP) Chapters 797 and 800 standards. Baseline sterile compounding training data were collected and reviewed for sterile compounding facilities across a multihospital health system, which included 37 distinct sterile compounding operations. Current sterile compounding personnel across the system completed preintervention assessments consisting of a written, knowledge-based exam; media-fill challenge test; and an observed assessment of aseptic technique. The personnel then completed refresher training of sterile compounding concepts by completing online and in-person courses. A postintervention assessment was then conducted to evaluate training methods and topics. Based on the intervention data, a training program for new sterile compounding personnel was developed and implemented. A program to provide annual, ongoing training to existing sterile compounding personnel was also developed and implemented. There was a statistically significant improvement in sterile compounding written exam scores ( < .0001) and aseptic technique observation scores ( < .0001) after implementation of refresher training. The validated training program was then included in the development and implementation of standardized training for all new and existing sterile compounding personnel across a multihospital health system. A standardized and consistent, sterile compounding training program was developed for all new and existing sterile compounding personnel incorporating a live, in-person training course, as well as online and hands-on training.
本研究的目的是在一个多医院系统中开发并实施一个标准化的无菌配制培训项目，该项目纳入无菌配制最佳实践建议，并确保符合美国药典（USP）第797章和第800章标准。收集并审查了一个多医院卫生系统中各无菌配制设施的基线无菌配制培训数据，该系统包括37个不同的无菌配制操作单元。系统内当前的无菌配制人员完成了干预前评估，包括一次基于知识的书面考试、培养基灌装挑战测试以及无菌技术的观察评估。然后，这些人员通过完成在线课程和面对面课程，完成了无菌配制概念的复习培训。随后进行了干预后评估，以评估培训方法和主题。根据干预数据，为新的无菌配制人员制定并实施了一个培训项目。还制定并实施了一个为现有无菌配制人员提供年度持续培训的项目。在实施复习培训后，无菌配制书面考试成绩（<.0001）和无菌技术观察成绩（<.0001）有统计学意义的提高。然后，经过验证的培训项目被纳入为一个多医院卫生系统中所有新的和现有的无菌配制人员开展的标准化培训的开发和实施中。为所有新的和现有的无菌配制人员制定了一个标准化且一致的无菌配制培训项目，该项目包括一个现场面对面培训课程以及在线和实践培训。
