在使用全身性糖皮质激素进行过渡后，用氨苯砜治疗重症婴儿大疱性类天疱疮。
Severe Infantile Bullous Pemphigoid Treated with Dapsone after Bridging with Systemic Glucocorticoid.
作者信息
Thomsen Kenneth, Deleuran Mette, Vestergaard Christian, Holm Mette, Riber-Hansen Rikke, Bech Rikke
机构信息
Department of Dermatology and Venerology, Aarhus University Hospital, Aarhus, Denmark.
Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.
出版信息
Case Rep Dermatol. 2019 Jun 26;11(2):187-193. doi: 10.1159/000501359. eCollection 2019 May-Aug.
We present a case of severe and treatment-refractory bullous pemphigoid in a 3-month-old child. After topical and systemic corticoid treatment proved inefficient, dapsone 0.75 mg/kg was added initially without success. Disease control was reached with dapsone 1.5 mg/kg in addition to both topical and systemic glucocorticoid treatment, leaving the child with several side effects of the glucocorticoid treatment.
我们报告了一例3个月大儿童的严重且治疗难治性大疱性类天疱疮。在局部和全身使用皮质类固醇治疗无效后，最初添加了0.75毫克/千克的氨苯砜，但未成功。除局部和全身糖皮质激素治疗外，使用1.5毫克/千克的氨苯砜实现了疾病控制，但该患儿出现了糖皮质激素治疗的多种副作用。
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