Nakagawa Takashi, Hara Hisao, Yamamoto Masaya, Matsushita Yumi, Hiroi Yukio
Department of Cardiology, National Center for Global Health and Medicine, Tokyo, Japan.
Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Heart Asia. 2019 Jun 26;11(2):e011166. doi: 10.1136/heartasia-2018-011166. eCollection 2019.
Paroxysmal atrial fibrillation could progress to permanent atrial fibrillation. Whether the transmitral inflow waves could be used to predict progression from paroxysmal atrial fibrillation to permanent atrial fibrillation is unknown. Therefore, we investigated the association between the transmitral inflow waves and progression of paroxysmal atrial fibrillation.
We performed a retrospective study by analysing clinical and echocardiographic data from 88 patients with paroxysmal atrial fibrillation. We excluded patients who had structural heart disease, significant valvular disease, cardiomyopathy, cardiac device implantation or a left ventricular ejection fraction <50%.
The patients with progression to permanent atrial fibrillation were more likely to be male and had lower peak A velocity than those without progression. After adjusting for covariates, lower peak A velocity remained the independent predictor of progression to permanent atrial fibrillation (p=0.025).
The A velocity could be useful for predicting progression to permanent atrial fibrillation in Asian people.
阵发性心房颤动可能会进展为永久性心房颤动。二尖瓣流入波是否可用于预测阵发性心房颤动向永久性心房颤动的进展尚不清楚。因此，我们研究了二尖瓣流入波与阵发性心房颤动进展之间的关联。
我们通过分析88例阵发性心房颤动患者的临床和超声心动图数据进行了一项回顾性研究。我们排除了患有结构性心脏病、严重瓣膜病、心肌病、心脏装置植入或左心室射血分数<50%的患者。
进展为永久性心房颤动的患者更可能为男性，且其A峰速度低于未进展的患者。在对协变量进行调整后，较低的A峰速度仍然是进展为永久性心房颤动的独立预测因素（p=0.025）。
A峰速度可能有助于预测亚洲人群进展为永久性心房颤动。
