IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, United Kingdom.
PLoS One. 2019 Jul 19;14(7):e0219781. doi: 10.1371/journal.pone.0219781. eCollection 2019.
The aim of this study was to synthesize evidence from systematic reviews, to summarise the effects of rehabilitation interventions for improving balance in stroke survivors.
We conducted an overview of systematic reviews (SRs). We included Cochrane Systematic Reviews and non-Cochrane Systematic Reviews of randomized-controlled clinical trials and not-randomized clinical trials, in all types of stroke, comparing the effects of interventions, control interventions and no interventions on balance-related outcomes. We conducted a comprehensive search of electronic databases, from inception to December 2017. Data extracted included: number and type of participants, type of intervention, control intervention, method of assessing risk of bias of primary studies, balance outcome measures and results of statistical meta-analyses. Methodological quality of included reviews was assessed using AMSTAR 2. A narrative description of the characteristics of the SRs was provided and results of meta-analyses summarised with reference to their methodological quality.
51 SRs (248 primary studies and 10,638 participants) met the inclusion criteria and were included in the overview. All participants were adults with stroke. A wide variety of different balance and postural control outcomes were included. 61% of SRs focussed on the effectiveness of physical therapy, 20% virtual reality, 6% electromechanical devices, 4% Tai-Chi, whole body vibration and circuit training intervention, and 2% cognitive rehabilitation. The methodology of 54% of SRs were judged to be of a "low or critically low" quality, 23% "moderate" quality and 22% "high" quality.
There are 51 SRs of evidence relating to the effectiveness of interventions to improve balance in people with stroke, but the majority of these are of poor methodological quality, limiting our ability to draw clear implications. Only 22% of these SRs were judged to be of high quality, highlighting the need to address important methodological issues within rehabilitation research.
本研究旨在综合系统评价证据,总结康复干预对改善脑卒中幸存者平衡的效果。
我们进行了系统评价综述。我们纳入了 Cochrane 系统评价和非 Cochrane 系统评价的随机对照临床试验和非随机对照临床试验,涵盖所有类型的脑卒中,比较了干预措施、对照干预措施和无干预措施对平衡相关结局的影响。我们对电子数据库进行了全面检索,检索时间从建库至 2017 年 12 月。提取的数据包括:参与者的数量和类型、干预类型、对照干预措施、对原始研究偏倚风险的评估方法、平衡结局测量和统计荟萃分析结果。使用 AMSTAR 2 评估纳入综述的方法学质量。提供了对综述特征的描述性说明,并根据其方法学质量总结了荟萃分析结果。
51 项系统评价(248 项原始研究和 10638 名参与者)符合纳入标准并被纳入综述。所有参与者均为脑卒中成年人。纳入了各种不同的平衡和姿势控制结局。61%的系统评价重点关注物理治疗的有效性,20%关注虚拟现实,6%关注机电设备,4%关注太极、全身振动和电路训练干预,2%关注认知康复。54%的系统评价的方法学质量被评为“低或极低”,23%评为“中”,22%评为“高”。
有 51 项关于干预措施改善脑卒中患者平衡的有效性的系统评价证据,但其中大多数的方法学质量较差,限制了我们从中得出明确结论的能力。仅有 22%的系统评价被评为高质量,这突出表明需要在康复研究中解决重要的方法学问题。