Department of Neurosurgery, Sir Run Run Shaw Hospital, The Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China.
Department of Neurosurgery, Sir Run Run Shaw Hospital, The Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China.
World Neurosurg. 2019 Nov;131:e149-e154. doi: 10.1016/j.wneu.2019.07.097. Epub 2019 Jul 16.
Chronic subdural hematoma (cSDH) is one of the most common illnesses seen in neurosurgery departments worldwide. For surgical treatment, some neurosurgeons prefer single burr hole craniostomy (SBHC), whereas others prefer double burr hole craniostomy (DBHC). We performed a meta-analysis to investigate whether DBHC is associated with increased risks of recurrence, complications and mortality compared with SBHC in patients with cSDH.
Retrospective observational trial or randomized controlled trial (RCT) studies concerning burr hole craniostomy to treat cSDH were systematically identified through a search of electronic databases: PubMed, Web of Science, Embase, and Cochrane. Inclusion and exclusion criteria were defined for the eligible studies. The random fixed-effects model was used when heterogeneity was indicated; otherwise, a fixed-effects model was adopted.
This meta-analysis included 12 studies, 3 of which were RCTs. Our findings can be summarized as follows. First, SBHC did not increase the risk of recurrence compared with DBHC in patients with cSDH (odds ratio [OR], 1.28; 95% confidence interval [CI], 0.92-1.78; P =0.07). Second, DBHC was not associated with an increased complication rate compared with SBHC in patients with cSDH (OR, 0.74; 95% CI, 0.20-2.76; P = 0.11). Third, DBHC did not increase mortality compared with SBHC in patients with cSDH (OR, 1.38; 95% CI, 0.55-3.46; P = 0.58).
This meta-analysis demonstrates that there are no significant differences in recurrence rate, complication rate, and morbidity between SBHC and DBHC in the treatment of patients with cSDH.
慢性硬脑膜下血肿(cSDH)是全球神经外科最常见的疾病之一。对于手术治疗,一些神经外科医生更喜欢单骨孔颅骨切开术(SBHC),而另一些则更喜欢双骨孔颅骨切开术(DBHC)。我们进行了一项荟萃分析,以调查在治疗 cSDH 的患者中,与 SBHC 相比,DBHC 是否与更高的复发风险、并发症和死亡率相关。
通过检索电子数据库:PubMed、Web of Science、Embase 和 Cochrane,系统地识别了关于颅骨钻孔术治疗 cSDH 的回顾性观察性试验或随机对照试验(RCT)研究。为合格研究定义了纳入和排除标准。当存在异质性时,使用随机固定效应模型;否则,采用固定效应模型。
这项荟萃分析包括 12 项研究,其中 3 项为 RCT。我们的研究结果可以总结如下。首先,在 cSDH 患者中,SBHC 并不比 DBHC 增加复发风险(比值比 [OR],1.28;95%置信区间 [CI],0.92-1.78;P=0.07)。其次,在 cSDH 患者中,DBHC 与 SBHC 相比,并发症发生率没有增加(OR,0.74;95%CI,0.20-2.76;P=0.11)。第三,在 cSDH 患者中,DBHC 与 SBHC 相比,死亡率没有增加(OR,1.38;95%CI,0.55-3.46;P=0.58)。
这项荟萃分析表明,在治疗 cSDH 的患者中,SBHC 和 DBHC 之间在复发率、并发症发生率和发病率方面没有显著差异。