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牙医和牙科助手的尿汞水平及肾功能早期变化

Urinary mercury levels and early changes in kidney function in dentists and dental assistants.

作者信息

Verschoor M A, Herber R F, Zielhuis R L

机构信息

Coronel Laboratory for Occupational and Environmental Health, Medical Faculty, University of Amsterdam, The Netherlands.

出版信息

Community Dent Oral Epidemiol. 1988 Jun;16(3):148-52. doi: 10.1111/j.1600-0528.1988.tb00563.x.

Abstract

Mercury exposure and renal function parameters were examined in 68 dentists and 64 dental assistants. The levels of mercury in urine were low: only three individuals exceeded 20 micrograms/l. Increased excretion of urinary proteins and increased activity of urinary enzymes were observed. This enhanced prevalence of renal function changes appeared not to be related to the mercury urine level, age, sex, or smoking and drinking habits. Only for men was a positive relation between the level of mercury in urine and the activity of beta-galactosidase found. The proteinuria may be due to one or more potential nephrotoxic agents used in dental practice.

摘要

对68名牙医和64名牙科助手进行了汞暴露和肾功能参数检查。尿汞水平较低:只有三人超过20微克/升。观察到尿蛋白排泄增加和尿酶活性增加。肾功能改变的这种较高患病率似乎与尿汞水平、年龄、性别或吸烟和饮酒习惯无关。仅在男性中发现尿汞水平与β-半乳糖苷酶活性之间存在正相关。蛋白尿可能是由于牙科实践中使用的一种或多种潜在肾毒性物质所致。

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