Hospital Infection Management Division, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, 100053, China.
School of Health Management and Education, Capital Medical University, Beijing, China.
BMC Geriatr. 2019 Jul 19;19(1):193. doi: 10.1186/s12877-019-1208-x.
The elderly inpatients are in high risk of suffering health-care associated infection (HAI). The study aimed to analyze the risk factors of health-care associated infection (HAI) in elderly hospitalized patients to prevent it and improve the recovery rate of elderly patients.
The study was a Retrospective Cohort Study based on a 3-year surveillance in elderly inpatients in a large tertiary hospital in China. A retrospective review of the elderly inpatients ≥60 years with or without HAI were conducted. Binary multivariable logistic regression was used to evaluate the potential association between HAI and risk factors.
We investigated a total of 60,332 subjects aged 60 years old or above. The incidence of HAI in elderly was 2.62%. With adjustment for some factors, advanced age, hospital days before HAI, intensive care unit (ICU) admission, use of ventilator, central line catheter or urinary catheter and cerebral hemorrhage, cerebral infarction, brain neoplasms, diabetes mellitus, coronary artery disease, malignant tumor and malignant hematonosis had significantly increased odds ratios (OR) of suffering from HAI compared with the control group but body weight and operation decreased OR.
Our findings suggested that advanced age, accompanied by some neurological and chronic noncommunicable diseases, hospital days before HAI, ICU admission, and use of devices were risk factors of suffering HAI in the elderly but the body weight and operation were the potential protective factors in this sample.
老年住院患者存在发生医院获得性感染（HAI）的高风险。本研究旨在分析老年住院患者发生医院获得性感染（HAI）的危险因素，以预防 HAI 并提高老年患者的康复率。
本研究是在中国一家大型三级医院对 3 年老年住院患者进行的回顾性队列研究。对有或无 HAI 的≥60 岁老年住院患者进行回顾性审查。采用二元多变量 logistic 回归评估 HAI 与危险因素之间的潜在关联。
我们共调查了 60332 名 60 岁及以上的受试者。老年患者 HAI 的发生率为 2.62%。经过一些因素的调整，与对照组相比，高龄、HAI 前住院天数、重症监护病房（ICU）入住、使用呼吸机、中心静脉导管或导尿管以及脑出血、脑梗死、脑肿瘤、糖尿病、冠心病、恶性肿瘤和恶性血液病显著增加了 HAI 的患病比值比（OR），而体重和手术则降低了 OR。
我们的研究结果表明，高龄、伴有某些神经和慢性非传染性疾病、HAI 前住院天数、入住 ICU 以及使用器械是老年患者发生 HAI 的危险因素，但在该样本中体重和手术是潜在的保护因素。
