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手术类型对老年股骨转子间骨折患者死亡率的影响:一项韩国全国队列研究。

The effect of surgery type on mortality in elderly patients with pertrochanteric femoral fracture: A Korean nationwide cohort study.

机构信息

Department of Preventive Medicine, Eulji University College of Medicine, Daejeon, South Korea.

Department of Orthopaedic Surgery, Eulji University Hospital, Daejeon, South Korea.

出版信息

Asian J Surg. 2020 Apr;43(4):550-556. doi: 10.1016/j.asjsur.2019.06.006. Epub 2019 Jul 16.

Abstract

BACKGROUND/OBJECTIVE: The purpose of this study is to analyze the effect of surgical methods on mortality and the relative risk of patients who underwent internal fixation (IF) or hemiarthroplasty (HA) after being diagnosed as a pertrochanteric fracture over 65 years old in a Korean nationwide cohort with a single insurance medical system.

METHODS

The Korean National Health Insurance Service-Senior cohort (NHIS-Senior, NHIS-2018-2-111) was used in this study. The eligibility criteria for incident hip fracture patients were the following: (1) first-time admission to acute care hospitals (index admission) with pertrochanteric fracture (ICD-10 S721), (2) three years of hip fracture-free period, (3) recipients of typical surgeries including IF, HA, (4) age between 65 and 99.

RESULTS

a total of 7223 patients were enrolled in the cohort. There were 1662 patients (23%) in the HA group and 5561 patients (77%) in the IF group. Mortality rates of the IF group and HA group were 13.46 and 17.94 cases per 100 person-years, respectively. In the multivariable-adjusted Cox proportional hazard model, the HA group had 1.22 times more hazard of all-cause mortality than IF group (aHR 1.22, 95% CI 1.13-1.32). In subgroup analysis, aged 65-79 and female patients showed a prominent association between surgery type and mortality (aHR 1.52, 95% CI 1.29-1.79).

CONCLUSIONS

In patients with pertrochanter fracture over 65 years, 1.22-fold mortality rate was observed when HA was performed compared to that of IF, and the difference in mortality was particularly prominent within 1-year after surgery.

摘要

背景/目的:本研究旨在分析在韩国单一保险医疗体系下,65 岁以上被诊断为股骨转子间骨折的患者接受内固定(IF)或半髋关节置换术(HA)治疗的手术方式对死亡率的影响及其相对风险。

方法

本研究使用了韩国国民健康保险服务-老年人队列(NHIS-Senior,NHIS-2018-2-111)。股骨转子间骨折患者的入选标准如下:(1)首次入住急性护理医院(索引入院),诊断为股骨转子间骨折(ICD-10 S721),(2)三年内无髋部骨折史,(3)接受典型手术治疗,包括 IF、HA,(4)年龄在 65 至 99 岁之间。

结果

该队列共纳入 7223 例患者。HA 组 1662 例(23%),IF 组 5561 例(77%)。IF 组和 HA 组的死亡率分别为 13.46 和 17.94 例/100 人年。多变量调整后的 Cox 比例风险模型显示,HA 组全因死亡率的风险比 IF 组高 1.22 倍(aHR 1.22,95%CI 1.13-1.32)。亚组分析显示,65-79 岁和女性患者的手术类型与死亡率之间存在显著关联(aHR 1.52,95%CI 1.29-1.79)。

结论

在 65 岁以上的股骨转子间骨折患者中,与 IF 相比,HA 术后的死亡率增加了 1.22 倍,并且术后 1 年内死亡率的差异尤为显著。

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