Pgp规则：一种基于决策树的P-糖蛋白底物和抑制剂预测服务器。 - Suppr | 超能文献

PgpRules: a decision tree based prediction server for P-glycoprotein substrates and inhibitors.

作者信息

Wang Pei-Hua, Tu Yi-Shu, Tseng Yufeng J

出版信息

Bioinformatics. 2019 Nov 1;35(21):4535. doi: 10.1093/bioinformatics/btz546.

DOI:10.1093/bioinformatics/btz546

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

PgpRules: a decision tree based prediction server for P-glycoprotein substrates and inhibitors.Pgp规则：一种基于决策树的P-糖蛋白底物和抑制剂预测服务器。

Bioinformatics. 2019 Nov 1;35(21):4535. doi: 10.1093/bioinformatics/btz546.

2

PgpRules: a decision tree based prediction server for P-glycoprotein substrates and inhibitors.PgpRules：一个基于决策树的 P-糖蛋白底物和抑制剂预测服务器。

Bioinformatics. 2019 Oct 15;35(20):4193-4195. doi: 10.1093/bioinformatics/btz213.

3

Prediction of P-glycoprotein substrates by a support vector machine approach.基于支持向量机方法的P-糖蛋白底物预测

J Chem Inf Comput Sci. 2004 Jul-Aug;44(4):1497-505. doi: 10.1021/ci049971e.

4

Development of decision tree models for substrates, inhibitors, and inducers of p-glycoprotein.P-糖蛋白底物、抑制剂和诱导剂的决策树模型开发。

Curr Drug Metab. 2009 May;10(4):339-46. doi: 10.2174/138920009788499021.

5

ADMET evaluation in drug discovery. 13. Development of in silico prediction models for P-glycoprotein substrates.药物发现中的ADMET评估。13. P-糖蛋白底物的计算机预测模型的开发。

Mol Pharm. 2014 Mar 3;11(3):716-26. doi: 10.1021/mp400450m. Epub 2014 Feb 18.

6

ADME evaluation in drug discovery. 10. Predictions of P-glycoprotein inhibitors using recursive partitioning and naive Bayesian classification techniques.药物发现中的 ADME 评估。10. 使用递归分区和朴素贝叶斯分类技术预测 P-糖蛋白抑制剂。

Mol Pharm. 2011 Jun 6;8(3):889-900. doi: 10.1021/mp100465q. Epub 2011 Mar 25.

7

Computer-assisted protein domain boundary prediction using the DomPred server.使用DomPred服务器进行计算机辅助蛋白质结构域边界预测。

Curr Protein Pept Sci. 2007 Apr;8(2):181-8. doi: 10.2174/138920307780363415.

8

Prediction and characterization of P-glycoprotein substrates potentially bound to different sites by emerging chemical pattern and hierarchical cluster analysis.通过新兴化学模式和层次聚类分析预测和表征可能与不同位点结合的P-糖蛋白底物

Int J Pharm. 2016 Apr 11;502(1-2):61-9. doi: 10.1016/j.ijpharm.2016.02.022. Epub 2016 Feb 17.

9

Computer evaluation of drug interactions with P-glycoprotein.

Bull Exp Biol Med. 2013 Feb;154(4):521-4. doi: 10.1007/s10517-013-1992-9.

10

Computational models for predicting substrates or inhibitors of P-glycoprotein.用于预测 P-糖蛋白底物或抑制剂的计算模型。

Drug Discov Today. 2012 Apr;17(7-8):343-51. doi: 10.1016/j.drudis.2011.11.003. Epub 2011 Nov 18.

引用本文的文献

1

Synthesis and Anticancer Activity of A-Ring-Modified Derivatives of Dihydrobetulin.A-环修饰的二氢葫芦素衍生物的合成及抗癌活性。

Int J Mol Sci. 2023 Jun 7;24(12):9863. doi: 10.3390/ijms24129863.

2

The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells.齐墩果醛-β-烯酮对多柔比星耐药癌细胞的细胞毒性分子机制

Biology (Basel). 2023 Mar 8;12(3):415. doi: 10.3390/biology12030415.

3

Combining Multi-Dimensional Convolutional Neural Network (CNN) With Visualization Method for Detection of Glover Infection in Cotton Leaves Using Hyperspectral Imaging.结合多维卷积神经网络（CNN）与可视化方法，利用高光谱成像检测棉花叶片中的格洛弗感染。

Front Plant Sci. 2021 Feb 15;12:604510. doi: 10.3389/fpls.2021.604510. eCollection 2021.