• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[血管内卒中治疗中的麻醉管理]

[Anesthesiological management in endovascular stroke treatment].

作者信息

Theilen H J, Gerber J C

机构信息

Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Carl-Gustav-Carus, Fetscherstr. 74, 01307, Dresden, Deutschland.

Institut und Poliklinik für Neuroradiologie, Universitätsklinikum Carl-Gustav-Carus, Fetscherstr. 74, 01307, Dresden, Deutschland.

出版信息

Anaesthesist. 2019 Nov;68(11):733-741. doi: 10.1007/s00101-019-0621-z.

DOI:10.1007/s00101-019-0621-z
PMID:31324931
Abstract

Early recanalization of the closed cerebral arteries after acute ischemic stroke (AIS) is the only treatment to minimize long-term disability and to reduce the associated morbidity and mortality. For a long time the only proven causal treatment of AIS was intravenous thrombolysis; however, after the publication of a series of randomized prospective studies concerning endovascular mechanical thrombectomy using stent retriever systems after AIS, new guidelines were published. It was found that endovascular treatment (EVT) dramatically improves the outcome of eligible patients. The stent retriever enables high recanalization rates by clot removal from the cerebral arterial system by means of aspiration of the thrombus via the catheter and/or by entrapping it with a stent system. The management of anesthesia during the procedure is indispensable to prevent hypoxia and hemodynamic instability; however, which form of anesthesia (i.e. general anesthesia vs. conscious sedation) is advantageous for the patient during EVT is controversially discussed. In the first studies using retrospective data conscious sedation resulted in a better outcome compared to general anesthesia following EVT; however, in prospective studies this finding could not be confirmed. To obtain optimal neurological results after AIS and EVT with general anesthesia, it is of tremendous importance not to delay the EVT due to the anesthesiology procedure. Furthermore, hypotension, hypovolemia and hypocapnia should also be strictly avoided. Finally, the optimal anesthesiological approach should be guided by the current clinical state and pre-existing comorbidities of the patient.

摘要

急性缺血性卒中(AIS)后闭塞脑动脉的早期再通是将长期残疾降至最低并降低相关发病率和死亡率的唯一治疗方法。长期以来,唯一经证实的AIS因果治疗方法是静脉溶栓;然而,在一系列关于AIS后使用支架取栓系统进行血管内机械取栓的随机前瞻性研究发表后,新的指南发布了。研究发现,血管内治疗(EVT)显著改善了符合条件患者的预后。支架取栓器通过经导管抽吸血栓和/或用支架系统捕获血栓,从脑动脉系统中清除血栓,从而实现高再通率。手术过程中的麻醉管理对于预防缺氧和血流动力学不稳定是必不可少的;然而,在EVT期间哪种麻醉方式(即全身麻醉与清醒镇静)对患者更有利,目前仍存在争议。在最初使用回顾性数据的研究中,与EVT后的全身麻醉相比,清醒镇静的结果更好;然而,在前瞻性研究中,这一发现未能得到证实。为了在全身麻醉下进行AIS和EVT后获得最佳神经学结果,至关重要的是不要因麻醉程序而延迟EVT。此外,还应严格避免低血压、低血容量和低碳酸血症。最后,最佳的麻醉方法应以患者当前的临床状态和既往合并症为指导。

相似文献

1
[Anesthesiological management in endovascular stroke treatment].[血管内卒中治疗中的麻醉管理]
Anaesthesist. 2019 Nov;68(11):733-741. doi: 10.1007/s00101-019-0621-z.
2
Endovascular thrombectomy in acute ischemic stroke: new treatment guide.急性缺血性卒中的血管内血栓切除术:新的治疗指南
Curr Opin Anaesthesiol. 2018 Aug;31(4):473-480. doi: 10.1097/ACO.0000000000000621.
3
Role of anesthesia in endovascular stroke therapy.麻醉在血管内卒中治疗中的作用。
Curr Opin Anaesthesiol. 2017 Oct;30(5):563-569. doi: 10.1097/ACO.0000000000000507.
4
Local anesthesia versus general anesthesia during endovascular therapy for acute stroke: a propensity score analysis.局部麻醉与全身麻醉在急性脑卒中血管内治疗中的比较:倾向评分分析。
J Neurointerv Surg. 2021 Mar;13(3):207-211. doi: 10.1136/neurintsurg-2020-015916. Epub 2020 Jun 2.
5
Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial.3D 支架取栓联合与单纯抽吸血栓清除术治疗急性缺血性脑卒中介入治疗的安全性和有效性:一项随机临床试验。
JAMA Neurol. 2018 Mar 1;75(3):304-311. doi: 10.1001/jamaneurol.2017.3967.
6
General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke).全身麻醉与清醒镇静用于急性缺血性卒中血管内治疗的比较:AnStroke试验(卒中期间的麻醉)
Stroke. 2017 Jun;48(6):1601-1607. doi: 10.1161/STROKEAHA.117.016554.
7
Safety and quality of endovascular therapy under general anesthesia and conscious sedation are comparable: results from the GOLIATH trial.全麻和清醒镇静下血管内治疗的安全性和质量具有可比性:GOLIATH 试验结果。
J Neurointerv Surg. 2019 Nov;11(11):1070-1072. doi: 10.1136/neurintsurg-2019-014712. Epub 2019 Mar 29.
8
General anesthesia versus conscious sedation for endovascular therapy in acute ischemic stroke: A systematic review and meta-analysis.全身麻醉与清醒镇静用于急性缺血性脑卒中血管内治疗的比较:系统评价和荟萃分析。
J Clin Neurosci. 2021 Apr;86:10-17. doi: 10.1016/j.jocn.2021.01.012. Epub 2021 Jan 25.
9
Techniques for endovascular treatment of acute ischemic stroke.血管内治疗急性缺血性脑卒中的技术。
Rev Neurol (Paris). 2017 Nov;173(9):594-599. doi: 10.1016/j.neurol.2017.09.005. Epub 2017 Oct 2.
10
Effect of General Anesthesia and Conscious Sedation During Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke: A Randomized Clinical Trial.血管内治疗期间全身麻醉和清醒镇静对急性缺血性脑卒中梗死体积和临床结局的影响:一项随机临床试验。
JAMA Neurol. 2018 Apr 1;75(4):470-477. doi: 10.1001/jamaneurol.2017.4474.

引用本文的文献

1
Application Analysis of Multidisciplinary Diagnosis and Treatment Nursing Mode Based on Doctor-Nurse-Integration for Stroke Patients Undergoing Emergency Intervention Surgery.基于医护一体化的多学科诊疗护理模式在急诊介入手术脑卒中患者中的应用分析
Emerg Med Int. 2022 Nov 11;2022:6299676. doi: 10.1155/2022/6299676. eCollection 2022.
2
Team Prenotification Reduces Procedure Times for Patients With Acute Ischemic Stroke Due to Large Vessel Occlusion Who Are Transferred for Endovascular Therapy.团队预先通知可减少因大血管闭塞而转至血管内治疗的急性缺血性卒中患者的手术时间。
Front Neurol. 2022 Jan 3;12:787161. doi: 10.3389/fneur.2021.787161. eCollection 2021.
3

本文引用的文献

1
Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment.缺血性脑卒中早期血压及脑卒中亚型对卒中后认知障碍的影响。
Stroke. 2018 Jul;49(7):1610-1617. doi: 10.1161/STROKEAHA.118.020827. Epub 2018 Jun 12.
2
A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less?一项关于急性病患者吸氧作用的系统评价:我们是否应该追求更低的氧浓度?
Biomed Res Int. 2018 May 14;2018:7841295. doi: 10.1155/2018/7841295. eCollection 2018.
3
Outcomes of Anesthesia Selection in Endovascular Treatment of Acute Ischemic Stroke.
[Perioperative stroke].
[围手术期卒中]
Anaesthesist. 2021 Jan;70(1):3-12. doi: 10.1007/s00101-020-00823-5.
血管内治疗急性缺血性脑卒中的麻醉选择结局。
J Neurosurg Anesthesiol. 2019 Jan;31(1):43-49. doi: 10.1097/ANA.0000000000000500.
4
2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.2018 急性缺血性脑卒中患者早期管理指南:美国心脏协会/美国卒中协会医疗保健专业人员指南。
Stroke. 2018 Mar;49(3):e46-e110. doi: 10.1161/STR.0000000000000158. Epub 2018 Jan 24.
5
Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging.6至16小时卒中的血栓切除术及灌注成像选择
N Engl J Med. 2018 Feb 22;378(8):708-718. doi: 10.1056/NEJMoa1713973. Epub 2018 Jan 24.
6
Effect of General Anesthesia and Conscious Sedation During Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke: A Randomized Clinical Trial.血管内治疗期间全身麻醉和清醒镇静对急性缺血性脑卒中梗死体积和临床结局的影响:一项随机临床试验。
JAMA Neurol. 2018 Apr 1;75(4):470-477. doi: 10.1001/jamaneurol.2017.4474.
7
Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.发病后 6 至 24 小时内进行取栓术治疗与缺损和梗死不匹配的脑卒中。
N Engl J Med. 2018 Jan 4;378(1):11-21. doi: 10.1056/NEJMoa1706442. Epub 2017 Nov 11.
8
Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke: The Stroke Oxygen Study Randomized Clinical Trial.常规低剂量吸氧对急性中风成年患者死亡和残疾的影响:中风氧疗研究随机临床试验
JAMA. 2017 Sep 26;318(12):1125-1135. doi: 10.1001/jama.2017.11463.
9
Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke.急性缺血性脑卒中患者的入院血糖及动脉内治疗效果
Stroke. 2017 May;48(5):1299-1305. doi: 10.1161/STROKEAHA.116.016071. Epub 2017 Apr 7.
10
Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy: A Randomized Clinical Trial.清醒镇静与全身麻醉对接受血管内血栓切除术的缺血性中风患者早期神经功能改善的影响:一项随机临床试验。
JAMA. 2016 Nov 15;316(19):1986-1996. doi: 10.1001/jama.2016.16623.