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青少年癌症幸存者的内化症状及其匹配对照。

Internalizing symptoms in AYA survivors of childhood cancer and matched comparisons.

机构信息

Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Division of Medical Oncology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.

出版信息

Psychooncology. 2019 Oct;28(10):2009-2016. doi: 10.1002/pon.5183. Epub 2019 Aug 5.

Abstract

OBJECTIVE

As the number of pediatric cancer survivors increases, so does our need to understand behavioral late effects. Prior studies show mixed results, with some noting increased emotional distress and psychiatric diagnoses in cancer survivors and others suggesting resilience. The purpose of our study was to evaluate internalizing symptoms such as anxiety and depression in young adult survivors of childhood cancer compared with matched classroom matched peers.

METHOD

We completed a multisource, cross-sectional examination of internalizing symptoms using a semistructured psychiatric interview with 18-year-olds with a history of pediatric cancer compared with age, race, and gender matched classroom peers who had been identified during the survivor's first year of treatment and their primary caregivers.

RESULTS

Fifty-seven young adult survivors of childhood cancer and 60 comparison peers participated. There were no significant differences between survivors and their peers on the basis of self- or parent-reported depressive or anxiety symptoms or number of psychiatric diagnoses.

CONCLUSIONS

Young adult survivors of childhood cancer and their parents did not report increased rates of anxiety or depression compared with their former classroom peers. Despite experiencing a major life challenge, this group of young adults with cancer did not report more current or past symptoms of internalizing psychopathology.

摘要

目的

随着儿童癌症幸存者人数的增加,我们越来越需要了解行为学晚期效应。先前的研究结果不一,有些研究表明癌症幸存者的情绪困扰和精神科诊断增加,而另一些研究则表明他们具有韧性。我们的研究目的是评估儿童癌症成年幸存者的内化症状,如焦虑和抑郁,与匹配的同班同学进行比较。

方法

我们使用半结构化精神科访谈对 18 岁的儿科癌症幸存者进行了多源、横断面的内化症状评估,与在幸存者治疗的第一年期间确定的、年龄、种族和性别相匹配的同班同学及其主要照顾者进行了比较。

结果

57 名儿童癌症幸存者和 60 名对照组参与者参与了研究。根据自我报告或父母报告的抑郁或焦虑症状或精神科诊断数量,幸存者和他们的同龄人之间没有显著差异。

结论

与他们以前的同班同学相比,儿童癌症幸存者及其父母并没有报告更高的焦虑或抑郁发生率。尽管经历了重大的生活挑战,但这群患有癌症的年轻成年人并没有报告更多当前或过去的内化精神病理学症状。

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