牙周病与全身疾病关系的荟萃分析和系统评价的方法学质量评估。

Methodological Quality Assessment of Meta-analyses and Systematic Reviews of the Relationship Between Periodontal and Systemic Diseases.

机构信息

Department of Dental Public Health, School of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

J Evid Based Dent Pract. 2019 Jun;19(2):131-139. doi: 10.1016/j.jebdp.2018.12.003. Epub 2019 Jan 2.

DOI:10.1016/j.jebdp.2018.12.003

PMID:31326045

Abstract

OBJECTIVES

The aims of this article are to identify all the published systematic reviews (SRs) and meta-analyses (MAs) that studied the relationship between periodontal and systemic diseases and to assess their quality using 2 scales (the Overview Quality Assessment Questionnaire [OQAQ] and A Measurement Tool to Assess Systematic Reviews [AMSTAR] checklist).

METHODS

For SRs and MAs to be included, they should have investigated one of the following systemic diseases: pulmonary conditions, cardiac conditions, endocrine conditions, cancer, blood disorders, psychological conditions, anxiety, depression, mood disorders, and several other diseases. Two investigators screened MEDLINE via PubMed, Embase, Scopus, Web of Science, and the Cochrane Database of Systematic Reviews. The tools used to evaluate quality were the AMSTAR scale and OQAQ. The protocol was prospectively registered in PROSPERO (CRD42018102208).

RESULTS

The search strategy found 691 unique articles, 42 of which met the eligibility criteria and were included in this review. Diabetes mellitus was the most investigated disease (14 out of 42 studies), followed by obesity (11 studies) and cardiovascular diseases (5 studies). A total of 40 reviews reported on the characteristics of included studies, and, as per the AMSTAR scale, 39 reviews had an a priori design. The number of reviews that fulfilled the status of publication criterion was the lowest (7 reviews only), followed by the number used in the assessment of publication bias (11 reviews). The number of high-quality reviews was higher with the OQAQ than with the AMSTAR checklist (33 vs 25 studies), but the AMSTAR showed a higher number of medium-quality reviews than the OQAQ (14 vs 6 studies). Both showed the same number of low-quality reviews.

CONCLUSIONS

High-quality SRs and MAs are crucial to understanding the relationship between systemic and periodontal diseases. Medical practitioners must be able to inform patients about oral health and specific periodontal health concerns.

摘要

目的

本文旨在确定所有研究牙周病和全身疾病之间关系的系统评价（SR）和荟萃分析（MA），并使用 2 个量表（概述质量评估问卷[OQAQ]和评估系统评价的测量工具[AMSTAR]清单）评估其质量。

方法

纳入的 SR 和 MA 应调查以下一种系统性疾病：肺部疾病、心脏疾病、内分泌疾病、癌症、血液疾病、心理疾病、焦虑、抑郁、情绪障碍以及其他几种疾病。两名调查员通过 PubMed 中的 MEDLINE、Embase、Scopus、Web of Science 和 Cochrane 系统评价数据库进行筛选。用于评估质量的工具是 AMSTAR 量表和 OQAQ。该方案在 PROSPERO（CRD42018102208）中进行了前瞻性注册。

结果

搜索策略共找到 691 篇独特的文章，其中 42 篇符合纳入标准并纳入本综述。糖尿病是研究最多的疾病（42 项研究中有 14 项），其次是肥胖症（11 项研究）和心血管疾病（5 项研究）。共有 40 篇综述报告了纳入研究的特征，根据 AMSTAR 量表，39 篇综述具有预先设计。仅满足出版标准状态的综述数量最少（仅 7 篇），其次是用于评估发表偏倚的综述数量（11 篇）。OQAQ 比 AMSTAR 清单显示出更高数量的高质量综述（33 项与 25 项研究），但 AMSTAR 显示出更高数量的中等质量综述（14 项与 6 项研究）。两者都显示出相同数量的低质量综述。