Izquierdo O A, Parsons C M, Baker D H
Department of Animal Sciences, University of Illinois, Urbana 61801.
Poult Sci. 1988 Feb;67(2):341-4. doi: 10.3382/ps.0670341.
Three chick growth assays were conducted to investigate the effects of monensin on lysine and arginine utilization in crossbred chicks (New Hampshire X Columbian). Chicks were fed either a low lysine corn-sesame meal diet containing graded increments of crystalline lysine.HCl (Assay 1) or an arginine-deficient casein-dextrose diet (Assay 2) supplemented with graded levels of L-arginine.HCl in the presence or absence of supplemental monensin (121 mg/kg). Based upon analysis by slope-ratio methodology (i.e., gain regressed on supplemental amino acid intake), the efficiency of L-lysine or L-arginine utilization was found to be the same in both monensin-fed and control chicks. In Assay 3, effects of monensin on the lysine-arginine antagonism were studied. Chicks were fed an arginine-deficient casein-dextrose diet supplemented with 1 or 2% L-lysine.acetate in the presence or absence of supplemental monensin. Growth performance was depressed by feeding both levels of supplemental L-lysine.acetate. Monensin had no effect on the magnitude of the growth depression caused by supplemental lysine. These results support the view that neither lysine nor arginine utilization is impaired by feeding monensin.
进行了三项雏鸡生长试验，以研究莫能菌素对杂交雏鸡（新汉普夏×哥伦比亚）赖氨酸和精氨酸利用的影响。雏鸡分别饲喂含不同梯度结晶赖氨酸盐酸盐的低赖氨酸玉米-芝麻粕日粮（试验1）或补充不同水平L-精氨酸盐酸盐的缺乏精氨酸的酪蛋白-葡萄糖日粮（试验2），同时添加或不添加莫能菌素（121mg/kg）。根据斜率比法分析（即生长量对补充氨基酸摄入量进行回归分析），发现饲喂莫能菌素的雏鸡和对照雏鸡对L-赖氨酸或L-精氨酸的利用效率相同。在试验3中，研究了莫能菌素对赖氨酸-精氨酸拮抗作用的影响。雏鸡饲喂缺乏精氨酸的酪蛋白-葡萄糖日粮，并在添加或不添加莫能菌素的情况下补充1%或2%的L-赖氨酸醋酸盐。饲喂两种水平的补充L-赖氨酸醋酸盐均会降低生长性能。莫能菌素对补充赖氨酸引起的生长抑制程度没有影响。这些结果支持了这样的观点，即饲喂莫能菌素不会损害赖氨酸或精氨酸的利用。
