Li Hongzhan, Wang Chunyan, Zhang Shaotian, Zhang Chengliang, Lu Rulan, Yun Wenwei, Zhou Xianju
1 Department of Neurology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
2 Laboratory of Neurological, Department of Neurology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.
J Int Med Res. 2019 Aug;47(8):3968-3971. doi: 10.1177/0300060519862950. Epub 2019 Jul 21.
Recently, repetitive transcranial magnetic stimulation (rTMS) has been widely used for treating neurological and psychiatric diseases. Low-frequency rTMS is used to effectively control the occurrence of seizures, including medication-refractory epilepsy and cortical dysplasia or neocortical epilepsy. However, there have been no reports on the effects of long-term rTMS on epilepsy. We observed the clinical effects of long-term rTMS in two drug-free adolescent epileptic patients with a preference for non-drug therapy. The two drug-free adolescent patients, who underwent intermittent low-frequency rTMS treatment for 36 weeks, obtained effective control of seizures (including episode and severity). However, a systematic study is required to confirm our observations.
最近，重复经颅磁刺激（rTMS）已被广泛用于治疗神经和精神疾病。低频rTMS可有效控制癫痫发作的发生，包括药物难治性癫痫、皮质发育异常或新皮质癫痫。然而，关于长期rTMS对癫痫影响的报道尚无。我们观察了长期rTMS对两名偏好非药物治疗的未服药青少年癫痫患者的临床效果。这两名未服药的青少年患者接受了为期36周的间歇性低频rTMS治疗，癫痫发作（包括发作次数和严重程度）得到了有效控制。然而，需要进行系统研究来证实我们的观察结果。
