Department of Surgery, University of California, San Francisco, San Francisco, Calif.
Department of Surgery, University of California, San Francisco, San Francisco, Calif; Division of Vascular and Endovascular Surgery, University of California, San Francisco, San Francisco, Calif.
J Vasc Surg. 2019 Nov;70(5):1419-1426. doi: 10.1016/j.jvs.2019.02.048. Epub 2019 Jul 18.
The objective of this study was to compare multibranched endovascular aneurysm repair (MBEVAR) of postdissection thoracoabdominal aortic aneurysms (TAAAs) and pararenal aortic aneurysms (PRAAs) with MBEVAR of degenerative TAAAs and PRAAs and to assess the role played by the preoperative correction of potential complicating factors, such as true lumen compression and false lumen origin of vital branches, using adjunctive maneuvers.
From July 2005 to July 2017, there were 162 patients who underwent elective MBEVAR of TAAAs and PRAAs. Data on demographics, procedural details, and outcomes were collected prospectively.
The mean age was 73 ± 8 years, and 119 of 162 (74%) were men; 19 of 162 (12%) had prior aortic dissections. Patients with dissections were younger (65 ± 11 years vs 74 ± 7 years; P = .002) and were less likely to have smoked (13/19 [68%] vs 135/143 [94%]; P = .002) or to have peripheral artery disease (0/19 [0%] vs 35/143 [24%]; P = .01) compared with those without dissections. Patients with prior dissections were more likely to have Crawford type II (10/19 [53%] vs 22/143 [15%]; P = .001) and type III (6/19 [32%] vs 16/143 [11%]; P = .03) TAAAs and were more likely to require at least one pre-MBEVAR adjunctive procedure (14/19 [74%] vs 55/143 [38%]; P = .006) compared with those without dissection. There was no difference in perioperative death, stroke, or paraplegia rates between the two groups. Median follow-up was 2.4 years (interquartile range, 0.8-4.7) and did not differ significantly between the two groups. There were no significant differences in branch vessel occlusion, endoleak rate, or aneurysm-related death between the two groups.
Patients with chronic type B aortic dissection are more likely to have extensive aneurysms and more likely to require adjunctive procedures to provide the appropriate anatomic substrate for MBEVAR, but this does not appear to affect the conduct of MBEVAR or its outcomes.
本研究旨在比较分支型腔内血管修复术(MBEVAR)治疗夹层胸主动脉瘤(TAAA)和肾周主动脉瘤(PRAAs)与 MBEVAR 治疗退行性 TAAA 和 PRAAs 的效果,并评估术前纠正潜在并发症(如真腔受压和假腔内脏分支起源)的作用,采用辅助操作。
2005 年 7 月至 2017 年 7 月,有 162 例患者接受了选择性 TAAA 和 PRAAs 的 MBEVAR。前瞻性收集人口统计学、手术细节和结果数据。
平均年龄为 73±8 岁,162 例患者中有 119 例(74%)为男性;19 例(12%)有既往主动脉夹层。夹层患者年龄较小(65±11 岁比 74±7 岁;P=0.002),吸烟(13/19 [68%]比 135/143 [94%];P=0.002)和外周动脉疾病(0/19 [0%]比 35/143 [24%];P=0.01)的可能性较小。既往有夹层的患者更可能为 Crawford Ⅱ型(10/19 [53%]比 22/143 [15%];P=0.001)和Ⅲ型(6/19 [32%]比 16/143 [11%];P=0.03)TAAA,更可能需要至少一种 MBEVAR 术前辅助操作(14/19 [74%]比 55/143 [38%];P=0.006),而无夹层的患者则无差异。两组间围手术期死亡率、卒中或截瘫率无差异。中位随访时间为 2.4 年(四分位距,0.8-4.7),两组间无显著差异。两组间分支血管闭塞、内漏率和动脉瘤相关死亡率无显著差异。
慢性 B 型主动脉夹层患者更可能患有广泛的动脉瘤,更可能需要辅助手术来为 MBEVAR 提供合适的解剖基础,但这似乎不会影响 MBEVAR 的实施或结果。