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夹层后主动脉瘤(PDAA)的血管内治疗策略。

Endovascular strategies for post-dissection aortic aneurysm (PDAA).

作者信息

Zeng Zhaoxiang, Zhao Yuxi, Wu Mingwei, Bao Xianhao, Li Tao, Feng Jiaxuan, Feng Rui, Jing Zaiping

机构信息

Department of Vascular Surgery, Changhai Hospital, Navy Medical University, 168 Changhai Road, Shanghai, 200433, People's Republic of China.

出版信息

J Cardiothorac Surg. 2020 Oct 1;15(1):287. doi: 10.1186/s13019-020-01331-8.

Abstract

Residual patent false lumen (FL) after type B aortic dissection (TBAD) repair is independently associated with poor long-term survival. Open surgery and endovascular repair result in good clinical outcomes in patients with AD. However, both treatments focus on proximal dissection but not distal dissection. About 13.4-62.5% of these patients present with different degrees of distal aneurysmal dilatation after primary repair. Although open surgery is the first-choice treatment for post-dissection aortic aneurysm (PDAA), there is a need for high technical demand since open surgery is associated with high mortality and morbidity. As a treatment strategy with minimal invasion, endovascular repair shows early benefits and low morbidity. For PDAA, the narrow true lumen (TL), rigid initial flap and branch arteries originating from FL have increased difficulties in operation. The aim of endovascular treatment is to promote FL thrombosis and aortic remodeling. Endovascular repair includes intervention from FL and TL sides. TL intervention techniques (parallel stent-graft, branched and fenestrated stent-graft among others) have been proven to be safe and effective in PDAA. Other FL intervention techniques that have been used in selected patients include FL embolization and candy-plug techniques. This article introduces available endovascular techniques and their outcomes for the treatment of PDAA.

摘要

B型主动脉夹层(TBAD)修复术后残留的有血流的假腔(FL)与长期生存不良独立相关。开放手术和血管腔内修复术在主动脉夹层(AD)患者中可带来良好的临床结果。然而,这两种治疗方法都侧重于近端夹层,而非远端夹层。这些患者中约13.4% - 62.5%在初次修复后出现不同程度的远端动脉瘤样扩张。虽然开放手术是夹层后主动脉瘤(PDAA)的首选治疗方法,但由于开放手术与高死亡率和高发病率相关,因此对技术要求很高。作为一种微创治疗策略,血管腔内修复术显示出早期益处且发病率低。对于PDAA,狭窄的真腔(TL)、僵硬的初始内膜瓣以及源自FL的分支动脉增加了手术难度。血管腔内治疗的目的是促进FL血栓形成和主动脉重塑。血管腔内修复包括从FL和TL侧进行干预。TL干预技术(如平行支架移植物、分支和开窗支架移植物等)已被证明在PDAA中是安全有效的。其他已在部分患者中使用的FL干预技术包括FL栓塞和糖果塞技术。本文介绍了用于治疗PDAA的可用血管腔内技术及其结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a1/7528487/8ac43cd4a1ae/13019_2020_1331_Fig1_HTML.jpg

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