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12个月大儿童维生素D缺乏与大运动发育之间存在关联吗?

Is There Any Relationship between Vitamin D Deficiency and Gross Motor Development in 12-Month-Old Children?

作者信息

Tavakolizadeh Reza, Ardalani Maryam, Shariatpanahi Ghazal, Mojtahedi Sayed Yousef, Sayarifard Azadeh

机构信息

Ziaeeyan Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Child Neurol. 2019 Summer;13(3):55-60.

Abstract

OBJECTIVE

We aimed to assess the possible relationship between vitamin D deficiency and gross motor developmental milestones in Iranian children in Tehran City, Iran.

MATERIALS & METHODS: In this cross-sectional study, 186 healthy children of one-yr-old age referring to a children hospital in Tehran, Iran from May 2015 to April 2016, were enrolled. The gross motor developmental milestone of children and their serum vitamin D concentration were evaluated.

RESULTS

Overall, 186 children, 92 males (49.5%) were studied. Twenty-four patients (12.9%) just were able to sit without support, and 40 patients (21.5%) to stand alone and to sit without support. Besides, 122 patients (65.6%) were able to walk with assistant or alone and to sit without support and stand alone. Vitamin D was sufficient in 148 children (79.6%), insufficient in 32 (17.2%) and deficient in 6 (3.2%). Sufficient vitamin D was significantly correlated with walking ability (<0.001, OR=3.9, 95%CI=1.9-8.4).

CONCLUSION

Considering the significant correlation between vitamin D deficiency and gross motor developmental milestones in this population of children, children referring to gross motor developmental delay need to be thoroughly evaluated for vitamin D deficiency.

摘要

目的

我们旨在评估伊朗德黑兰市儿童维生素D缺乏与大运动发育里程碑之间的可能关系。

材料与方法

在这项横断面研究中,纳入了2015年5月至2016年4月期间前往伊朗德黑兰一家儿童医院就诊的186名一岁健康儿童。评估了儿童的大运动发育里程碑及其血清维生素D浓度。

结果

总体而言,共研究了186名儿童,其中92名男性(49.5%)。24名患者(12.9%)仅能在无支撑的情况下坐立,40名患者(21.5%)能独自站立且在无支撑的情况下坐立。此外,122名患者(65.6%)能够在他人协助下或独自行走,且在无支撑的情况下坐立和独自站立。148名儿童(79.6%)维生素D充足,32名(17.2%)不足,6名(3.2%)缺乏。维生素D充足与行走能力显著相关(<0.001,OR=3.9,95%CI=1.9-8.4)。

结论

鉴于该儿童群体中维生素D缺乏与大运动发育里程碑之间存在显著相关性,对于存在大运动发育迟缓的儿童,需要对维生素D缺乏进行全面评估。

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