LIM 23 do Instituto de Psiquiatria do Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo , São Paulo , Brazil.
LIM 44 do Departamento de Radiologia do Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo , São Paulo , Brazil.
COPD. 2019 Aug;16(3-4):246-253. doi: 10.1080/15412555.2019.1634683. Epub 2019 Jul 22.
The postural imbalance is an extra-pulmonary condition, associated with chronic obstructive pulmonary disease (COPD). COPD affects older individuals and it is unclear whether balance abnormalities can be described as pathophysiological mechanism or aging. The present study aimed to evaluate the influence of age or disease on postural balance of patients with COPD. Patients with COPD over 50 years old were compared with age- and sex-matched healthy adults, and with sex-matched younger healthy adults ( = 30 in each group). The Modified Sensory Organization Test (mSOT) was performed in four different conditions fixed or sway-referenced surface both either with full or no vision. It was analyzed the center of pressure (CoP) variables: amplitude, velocity, root-mean-square and load asymmetry. Three-way ANOVA and post hoc analysis were performed been represented of age (older or COPD compared with younger healthy adults) or disease influences (COPD compared with older healthy groups). Main results were as follows: The CoP excursion was faster, with higher amplitude and variability progressively from COPD vs. older healthy vs. younger healthy adults ( < 0.05) showing age and disease influences ( < 0.05). Age and disease influences were also observed in the sway-referenced surface in both vision conditions. Impairment in postural balance was found related to aging and disease in patients with COPD older than 50 years.
姿势平衡失调是一种肺部以外的病症，与慢性阻塞性肺疾病（COPD）有关。COPD 影响老年人，目前尚不清楚平衡异常是否可以被描述为病理生理机制或衰老。本研究旨在评估年龄或疾病对 COPD 患者姿势平衡的影响。将 50 岁以上的 COPD 患者与年龄和性别匹配的健康成年人以及与性别匹配的年轻健康成年人（每组 30 人）进行比较。在四种不同条件下进行改良感觉组织测试（mSOT）：固定或摇摆参考表面，分别有或没有视觉。分析了以下压力中心（CoP）变量：振幅、速度、均方根和负载不对称性。进行了三因素方差分析和事后分析，代表年龄（与年轻健康成年人相比，年龄较大或 COPD）或疾病影响（与年龄较大的健康组相比，COPD）。主要结果如下：与年轻健康成年人相比，COPD 患者的 CoP 移动速度更快，幅度和变异性更高（ < 0.05），表明年龄和疾病有影响（ < 0.05）。在有或没有视觉的摇摆参考表面条件下，也观察到了年龄和疾病的影响。发现 50 岁以上的 COPD 患者的姿势平衡受损与衰老和疾病有关。
