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体外心肺复苏术治疗溶栓治疗无效的暴发性肺栓塞患者。

Extracorporeal cardiopulmonary resuscitation in a patient with fulminant pulmonary embolism refractory to intraarrest thrombolysis.

机构信息

Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.

Department of Thoracic and Cardiovascular Surgery, Heart & Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Perfusion. 2020 Mar;35(2):163-165. doi: 10.1177/0267659119862932. Epub 2019 Jul 21.

Abstract

INTRODUCTION

A fulminant pulmonary embolism is a potentially reversible cause of cardiac arrest with a reported mortality rate of up to 95%. Therapeutic strategies for fulminant pulmonary embolism continue to evolve.

CASE REPORT

We present a case of a 38-year-old female who suffered an in-hospital cardiac arrest due to fulminant pulmonary embolism. Extracorporeal cardiopulmonary resuscitation (facilitated by the LUCAS mechanical chest compression device) was successfully performed in this patient following failure of intraarrest thrombolysis.

DISCUSSION

For the management of fulminant pulmonary embolism, utilization of clot-directed therapies, especially intraarrest thrombolysis, has garnered increasing traction and interest. However, this therapeutic approach has its limitations. Fortuitously, the emergence of extracorporeal cardiopulmonary resuscitation has added a new dimension to the treatment of fulminant pulmonary embolism. A protocolized approach to treatment can improve outcomes in these patients.

CONCLUSION

Extracorporeal cardiopulmonary resuscitation can be used as a salvage therapy in patients with fulminant pulmonary embolism in whom intraarrest thrombolysis has failed.

摘要

简介

暴发性肺栓塞是心搏骤停的一个潜在可逆转病因,其死亡率高达 95%。暴发性肺栓塞的治疗策略不断发展。

病例报告

我们报告了一例 38 岁女性患者,因暴发性肺栓塞在院内发生心搏骤停。在该患者心搏骤停期间溶栓失败后,使用 LUCAS 机械胸部按压装置成功进行了体外心肺复苏。

讨论

对于暴发性肺栓塞的管理,使用以血栓为导向的治疗方法,特别是心搏骤停期间溶栓,已引起越来越多的关注和兴趣。然而,这种治疗方法有其局限性。幸运的是,体外心肺复苏的出现为暴发性肺栓塞的治疗增添了新维度。治疗方案的规范化可以改善这些患者的结局。

结论

对于心搏骤停期间溶栓失败的暴发性肺栓塞患者,可将体外心肺复苏用作挽救性治疗。

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