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研究技术简介:临床试验中的远程皮肤病学。

Research Techniques Made Simple:Teledermatology in Clinical Trials.

机构信息

Department of Dermatology, University of Utah, Salt Lake City, Utah, USA.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

J Invest Dermatol. 2019 Aug;139(8):1626-1633.e1. doi: 10.1016/j.jid.2019.04.004.

Abstract

Telemedicine is well established as a means of providing high-quality healthcare at a distance, particularly to patients in underserved populations. Technologies in teledermatology can be used to complement traditional methodologies of clinical trials, expanding accessibility of trials to people typically unable to participate in research. Tools of communication technology may enhance many aspects of clinical trials in dermatology, from recruitment and retention of participants to collection of real-time data. Clinical trials can be made completely virtual or incorporate aspects of virtual technologies at any stage of research. Virtual clinical trials are considered highly patient-centered, as the ability of participants to engage with research staff from their own home often supplants the need for many or all on-site clinic visits. As technological advances influence every aspect of modern life, clinical trials will also evolve to incorporate these tools, meeting participant expectations and overcoming traditional challenges of conducting research. Virtual clinical trials come with specific issues pertaining to analysis of data, technology, and oversight. As more virtual trials are conducted, advantages and limitations of using such technology in research will become clearer and regulatory guidelines will be more firmly established.

摘要

远程医疗作为一种提供高质量医疗服务的手段已经得到广泛认可,尤其是对于服务不足的人群中的患者。远程皮肤病学技术可用于补充临床试验的传统方法,扩大试验对通常无法参与研究的人群的可及性。通信技术工具可以增强皮肤病学临床试验的许多方面,从参与者的招募和保留到实时数据的收集。临床试验可以完全虚拟,也可以在研究的任何阶段结合虚拟技术的各个方面。虚拟临床试验被认为是高度以患者为中心的,因为参与者能够从自己的家中与研究人员进行互动,这往往取代了对许多或所有现场诊所就诊的需求。随着技术进步影响现代生活的各个方面,临床试验也将发展,纳入这些工具,满足参与者的期望,并克服进行研究的传统挑战。虚拟临床试验在数据分析、技术和监督方面存在特定问题。随着更多的虚拟试验的进行,使用这种技术进行研究的优势和局限性将更加清晰,监管指南也将更加牢固地确立。

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