Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Human Genome Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.
Complement Ther Med. 2019 Aug;45:7-13. doi: 10.1016/j.ctim.2019.05.011. Epub 2019 May 11.
In Kampo medicine, a traditional medicine pattern refers to the complete clinical presentation of the patient at a given moment in time. Candidate herbal formulas are chosen for a chief complaint, and an appropriate formula is determined on the basis of the pattern diagnosis. In this study, we demonstrated the importance of accompanying symptoms in diagnosing traditional medicine patterns.
Single centre observational study.
We analysed data from 524 new patients with a hypersensitivity to cold sensation as their primary diagnosis (mean age 51.6 ± 17.8 years; female ratio 82.1%) who visited the Keio University Hospital Kampo Clinic between 2008 and 2013.
Accompanying symptoms were recorded on the browser-based e-questionnaire system, which contained 128 items. The Japan Society for Oriental Medicine's board certified Kampo specialists diagnosed the traditional medicine patterns.
When participants were classified according to the origin of their cold sensation, there were no differences in their traditional medicine patterns. In contrast, when patients were classified based on the number of accompanying symptoms, a significant difference in the patterns was identified. An increasing number of accompanying symptoms was associated with more frequent qi stagnation and blood stasis pattern. Patients with a qi stagnation pattern had higher rates of depression and insomnia. In contrast, patients with a blood stasis pattern, had higher rates of acne, body stiffness, and menstrual abnormality.
Qi stagnation and blood stasis patterns are related to a number of different accompanying symptoms in the patients with hypersensitivity to cold sensation.
在汉方医学中，一种传统医学模式是指患者在特定时刻的完整临床表现。针对主要症状选择候选草药配方，并根据模式诊断选择合适的配方。本研究旨在强调伴随症状在诊断传统医学模式中的重要性。
单中心观察性研究。
我们分析了 2008 年至 2013 年间在庆应义塾大学医院汉方诊所就诊的 524 例以怕冷感为主要诊断的新患者（平均年龄 51.6±17.8 岁；女性比例 82.1%）的数据。
基于浏览器的电子问卷系统记录伴随症状，该系统包含 128 项内容。日本东方医学学会认证的汉方专家进行传统医学模式诊断。
当根据冷感来源对参与者进行分类时，他们的传统医学模式没有差异。相比之下，当根据伴随症状的数量对患者进行分类时，模式存在显著差异。伴随症状数量的增加与更频繁的气滞血瘀模式相关。气滞模式的患者抑郁和失眠的发生率更高。相比之下，血瘀模式的患者痤疮、身体僵硬和月经异常的发生率更高。
在对冷感敏感的患者中，气滞和血瘀模式与许多不同的伴随症状相关。
