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[疟疾:预防输血性疟疾的免疫许可管理]

[Malaria: immuno-permissive management in the prevention of transfusional malaria].

作者信息

Houzé S

机构信息

CNR du Paludisme, hôpital Bichat, AP-HP, 46, rue Henri Huchard, 75018 Paris, France.

出版信息

Transfus Clin Biol. 2019 Sep;26(3):192-194. doi: 10.1016/j.tracli.2019.07.002. Epub 2019 Jul 10.

Abstract

Malaria is a potentially life-threatening tropical infectious disease caused by a parasite that infects erythrocytes. Its transmission is vectorial, but the transfusion of infected red blood cells can cause a delicate diagnosis of transmitted malaria. Prevention is based on the selection of donors at risk by the search for antibodies reflecting past infection, in the absence of a sufficiently sensitive parasite detection technique to prevent all risks. Recent cases of transfusion malaria have reiterated that this preventive measure does not allow screening of all asymptomatic carriers.

摘要

疟疾是一种由感染红细胞的寄生虫引起的、可能危及生命的热带传染病。其传播通过病媒进行,但输注受感染的红细胞会导致对传播性疟疾的诊断变得棘手。预防措施基于通过寻找反映既往感染的抗体来筛选有风险的献血者,因为目前尚无足够灵敏的寄生虫检测技术来预防所有风险。近期的输血疟疾病例再次表明,这种预防措施无法筛查出所有无症状携带者。

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