Homocysteinemia as a cause for amaurosis fugax in a patient without an apparent embolic source.

To report a case with monocular transient vision loss (TVL) associated with Hyperhomocysteinemia. We present a case with persistent TVL attacks and high level of homocysteine. A 32-year-old male had a history of episodes of recurrent monocular TVL. Extensive ophthalmic, systemic and laboratory studies were unremarkable with the exception of high plasma homocysteine level. He never experienced TVL during the 36-month follow-up after starting folate, B12 and B6 except for one episode in which he had discontinued the treatment for three months. This case may suggest hyperhomocysteinemia as one of the underlying causes of recurrent attacks of TVL without any known source of emboli.