Westlander Göran, Schmidt Johanna, Westin Cecilia
Livio Fertilitetscentrum Göteborg - Göteborg, Sweden Fertililitetscentrum - Fertilitetscentrum Göteborg, Sweden.
Livio Fertilitetscentrum Göteborg - Göteborg, Sweden Livio Fertilitetscentrum Göteborg - Göteborg, Sweden.
Lakartidningen. 2019 Jul 19;116:FL9I.
The most severe form of male infertility is non obstructive azoospermia (NOA), where spermatogenesis is impaired or absent. If testicular sperm can be retrieved, men with NOA can become biological fathers with IVF/ ICSI. In Sweden, testicular sperm aspiration (TESA) is the most common method used to retrieve sperm but is only successful in up to 34% of procedures. In 2013, our fertility center introduced MD-TESE, where an operating microscope is used to target the biopsies. We have performed more than 134 MD-TESE procedures, mainly in cases where TESA sperm recovery failed previously. Sperm sufficient for ICSI were recovered in 52 % and in these cases 75 % resulted in embryo transfer, resulting in a 34 % ongoing pregnancy rate/deliveries per transfer. Results are encouraging and hopefully more Swedish IVF centers will introduce this technique.
男性不育最严重的形式是非梗阻性无精子症（NOA），即精子发生受损或不存在。如果能够获取睾丸精子，患有NOA的男性可以通过体外受精/卵胞浆内单精子注射（IVF/ICSI）成为生物学意义上的父亲。在瑞典，睾丸精子抽吸术（TESA）是最常用的获取精子的方法，但在高达34%的手术中才会成功。2013年，我们的生育中心引入了显微外科睾丸精子提取术（MD-TESE），该方法使用手术显微镜来定位活检组织。我们已经进行了134多次MD-TESE手术，主要针对之前TESA取精失败的病例。52%的手术成功获取了足够用于ICSI的精子，在这些病例中*~* 75%进行了胚胎移植，每次移植的持续妊娠率/分娩率为34%。结果令人鼓舞，希望更多瑞典的体外受精中心将引入这项技术。
