Kurihara Yuichi, Furue Masutaka
Department of Dermatology, Steel Memorial Yawata Hospital, 1-1-1 Harunomachi, Yahatahigashi-ku, Kitakyushu, 805-8508, Japan.
Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
BMC Dermatol. 2019 Jul 23;19(1):11. doi: 10.1186/s12895-019-0091-7.
Hidradenitis suppurativa is one member of the follicular occlusion triad: acne conglobata, hidradenitis suppurativa, and dissecting cellulitis of the scalp. The presence of acantholysis and desmoglein autoantibodies in hidradenitis suppurativa is rare.
We report a case of 68-year-old male with a diagnosis of gluteal hidradenitis suppurativa co-presenting pemphigus-like findings including acantholysis and positive desmoglein autoantibodies.
To our knowledge, comorbidity of gluteal hidradenitis suppurativa and pemphigus-like findings has not been reported before. This case implies a relationship between two different conditions; the follicular occlusion triad and pemphigus, highlighting a potential induction of pemphigus-like lesion by chronic inflammatory process.
化脓性汗腺炎是毛囊闭锁三联征的一种：聚合性痤疮、化脓性汗腺炎和头皮穿掘性蜂窝织炎。化脓性汗腺炎中出现棘层松解和桥粒芯糖蛋白自身抗体的情况较为罕见。
我们报告一例68岁男性，诊断为臀部化脓性汗腺炎，同时伴有类天疱疮样表现，包括棘层松解和桥粒芯糖蛋白自身抗体阳性。
据我们所知，臀部化脓性汗腺炎与类天疱疮样表现的合并症此前尚未见报道。该病例提示了两种不同病症之间的关联；毛囊闭锁三联征和天疱疮，突出了慢性炎症过程可能诱发类天疱疮样病变。
