小儿器官捐献者的管理
Management of the Pediatric Organ Donor.
作者信息
Beckman Elizabeth J
出版信息
J Pediatr Pharmacol Ther. 2019 Jul-Aug;24(4):276-289. doi: 10.5863/1551-6776-24.4.276.
Abstract
Management of the pediatric organ donor necessitates understanding the physiologic changes that occur preceding and after death determination. Recognizing these changes allows application of the therapeutic strategies designed to optimize hemodynamics and metabolic state to allow for preservation of end-organ function for maximal organ recovery and minimal damage to the donor grafts. The pediatric pharmacist serves as the medication expert and may collaborate with the organ procurement organizations for provision of pharmacologic hemodynamic support, hormone replacement therapy, antimicrobials, and nutrition for the pediatric organ donor.
摘要
小儿器官捐献者的管理需要了解死亡判定前后发生的生理变化。认识到这些变化有助于应用旨在优化血流动力学和代谢状态的治疗策略，从而保护终末器官功能，以实现最大程度的器官恢复并使供体移植物受到的损害最小化。小儿药剂师作为用药专家，可能会与器官获取组织合作，为小儿器官捐献者提供血流动力学药物支持、激素替代疗法、抗菌药物和营养支持。
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