Woo Won-Sik, Joo Min Soo, Hwang Jee Youn, Kwon Mun-Gyeong, Seo Jung Soo, Hwang Seong Don, Jee Bo-Yeong, Kim Mu-Chan, Park Chan-Il
Institute of Marine Industry, College of Marine Science, Gyeongsang National University, 455, Tongyeong 650-160, Republic of Korea.
Aquatic Animal Disease Control Center, National Institute of Fisheries Science (NIFS), 216 Gijanghaean-ro, Gijang-eup, Gijang-gun, Busan 46083, Republic of Korea.
Data Brief. 2019 Apr 23;25:103943. doi: 10.1016/j.dib.2019.103943. eCollection 2019 Aug.
CXCL10 plays an important role in angiogenesis and inhibits the differentiation of endothelial cells into capillaries. It also plays an important role in the generation and transmission of effector T cell responses and the recruitment of T cells to inflammatory sites. In this article, we constructed cDNAs to identify and analyse the CXCL10 domain, and performed multiple alignments and a phylogenetic analysis to determine homology with other animals. Real-time PCR was performed to confirm construction and expression after bacterial and viral infection.
CXCL10在血管生成中起重要作用,并抑制内皮细胞分化为毛细血管。它在效应T细胞反应的产生和传递以及T细胞募集到炎症部位的过程中也发挥重要作用。在本文中,我们构建了cDNA以鉴定和分析CXCL10结构域,并进行了多序列比对和系统发育分析以确定与其他动物的同源性。进行实时PCR以确认细菌和病毒感染后的构建和表达情况。