Dechsupa Nathupakorn, Kantapan Jiraporn, Tungjai Montree, Intorasoot Sorasak
Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 110 Intawaroros Rd., Sripoom, Chiang Mai, 50200, Thailand.
Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 110 Intawaroros Rd., Sripoom, Chiang Mai, 50200, Thailand.
Heliyon. 2019 Jul 11;5(7):e02052. doi: 10.1016/j.heliyon.2019.e02052. eCollection 2019 Jul.
In this study, the Maprang ( Griffith) seeds of 3 Thai varieties of this plant were studied in terms of nutrition, phytochemicals, chemical antioxidants and the bioactivity of their extracts. Maprang seeds revealed high levels of carbohydrates, dietary fiber, energy, potassium, phosphorus, magnesium, and calcium. The Maprang seed extracts possessed a high polyphenolic content and exhibited antioxidant properties against DPPH˙, ABTS˙, and ferric reduction. Additionally, 18-compounds were charaterized by RP-HPLC-DAD with two being recognized as gallic acid and ellagic acid and 16-unknown gallotannins. The HPLC fingerprint was composed of 4 major compounds. The extract showed active growth inhibition against leukemia, lung cancer cell lines and for 15 strains of bacteria. It is known to be particularly effective in drug resistant cells. Our results indicated that maprang seeds are a new natural source of nutrition, minerals and phytochemicals that may be applicable for use as a food supplement and as an effective drug in the treatment of certain diseases.
在本研究中，对该植物3个泰国品种的芒普朗（格里菲思）种子进行了营养成分、植物化学物质、化学抗氧化剂及其提取物生物活性方面的研究。芒普朗种子显示出高水平的碳水化合物、膳食纤维、能量、钾、磷、镁和钙。芒普朗种子提取物具有高多酚含量，并对DPPH˙、ABTS˙和铁还原表现出抗氧化特性。此外，通过反相高效液相色谱-二极管阵列检测（RP-HPLC-DAD）鉴定出18种化合物，其中两种被确认为没食子酸和鞣花酸，16种为未知的没食子鞣质。高效液相色谱指纹图谱由4种主要化合物组成。该提取物对白血病、肺癌细胞系以及15种细菌菌株表现出活性生长抑制作用。已知其在耐药细胞中特别有效。我们的结果表明，芒普朗种子是营养、矿物质和植物化学物质的新天然来源，可作为食品补充剂使用，并作为治疗某些疾病的有效药物。
